Injury roundup: Chiefs hit hard with loss of Charles … but KC not alone

The Kansas City Chiefs lost the worst possible player to a potentially devastating knee injury in the first round of Sunday’s games. The New York Giants lost a trio of players at the worst possible time in the final game of the evening.

If the preliminary diagnosis on Jamaal Charles’ injured right knee is correct, the Chiefs’ Pro Bowl running back could be done for the season with a torn ACL.

Charles’ knee buckled as he tried to cut to the left in the third quarter of Kansas City’s 18-17 loss to the visiting Chicago Bears in Week 5. Charles will have an MRI exam on Monday.

He missed most of the 2012 season after tearing the ACL in his left knee.

On Sunday night, the Giants, playing host to the struggling 49ers in the final game of the day, lost linebacker Jon Beason to a concussion early in the game and he did not return.

Then as Eli Manning & Co. attempted to mount the game-winning drive while down four points in the game’s closing minutes, receivers Odell Beckham Jr. and Ruben Randle were on the bench. Beckham seemed to tweak his hamstring on an earlier touchdown catch.

Beckham actually returned to the game on that final Giants drive, and drew a pass interference call to set up the game-winning TD pass to Larry Donnell with 21 seconds to play in the 30-27 Giants win.

NFL WEEK 17

In other injury news:

— A pair of pass rushers, DeMarcus Ware of the Broncos, and Elvis Dumervil of the Ravens, left Sunday games early. Ware exited on a cart with an injured back during the first half of Denver’s game at Oakland; Dumervil hurt his groin in the first half against Cleveland, and was joined on Baltimore’s sideline by defensive backs Lardarius Webb (thigh) and Will Davis (knee).

— The Patriots (Dont’a Hightower; rib), Bears (Shea McClellin; knee), Cardinals (Alex Okafor and Kenny Demens, both knees) and Lions (DeAndre Levy; hip) lost linebackers, too.

— Browns CB Joe Haden banged his head in the fourth quarter and was kept out with a concussion.

— Another corner, Davon House of the Jaguars, was using a cane in the locker room after hurting his hip against the Bucs. Jacksonville also had two running backs leave: T.J. Yeldon (groin) and Bernard Pierce. For the Bucs, FS Chris Conte left after hurting his ankle.

— Falcons C Mike Person left with an ankle sprain, and WR Leonard Hankerson returned despite a rib injury, two players who won’t get much time to heal because Atlanta plays at New Orleans on Thursday night.

— Raiders DE Justin Tuck left with a shoulder injury.

— The Rams and Packers each lost key players on both sides of the ball in their game, with St. Louis seeing G Roger Saffold (shoulder) and DL Chris Long (knee) get injured, while Green Bay G T.J. Lang (knee), DT B.J. Raji (groin) and LB Nick Perry (shoulder) out.

— Other skill players who left games: Saints WR Marques Colston (arm injury), Redskins RB Matt Jones (sprained toe) and Bills RB Cierre Wood (knee).