Padres hit franchise-record 7 home runs en route to 5th straight win
Hedges hit his first career slam and drove in five runs. Myers went 2 for 2, drove in four and scored four times, and Renfroe had four hits, scored four and drove in three.
Myers hit the team-record seventh homer in a five-run eighth that included homers by Hosmer and Renfroe off Sam Gaviglio.
The Padres nearly matched the franchise record of 20 runs, done twice and most recently in Montreal in 2001.
San Diego put two on and two outs in the ninth against Luke Maile, a catcher who pitched the final inning. Hedges, the San Diego catcher, took three strikes to end the inning. Maile began the inning by getting Renfroe to look at strike three.
Rookie Cal Quantrill (1-2), from nearby Port Hope, Ontario, and the son of former Blue Jays and Padres pitcher, Paul Quantrill, went six innings to earn his first major league win in his fourth career start.
The 24-year-old right-hander struck out a career-high nine, while surrendering three earned runs on homers by Lourdes Gurriel Jr. and Justin Smoak, the only hits Quantrill allowed.
Myers and Kinsler hit back-to-back home runs in the second. Hedges launched San Diego’s first slam of the season in the fourth.
Rookie Josh Naylor, from nearby Mississauga, Ont., had given the Padres a first-inning lead with his first big league hit in his second career game, an RBI double. Naylor and Hosmer each had three of the Padres’ 20 hits.
In his third start of the year, Jackson was roughed up for the second straight game. After surrendering six runs over five innings to Boston on Monday, the right-hander lasted just four innings, giving up seven earned runs on seven hits.
Padres: OF Franmil Reyes, San Diego’s leading home run hitter with 15, was given the day off Saturday to rest his knees. He tore his meniscus back in November in the Dominican Winter League and manager Andy Green opted to play it safe on the artificial turf of Rogers Centre. Naylor replaced him in right field.
Padres rookie RHP Chris Paddack (4-2, 1.93) faces Blue Jays RHP Marcus Stroman (2-6, 2.81) on Sunday. Paddack makes his second interleague start, having picked up the win back on April 24 against Seattle. Stroman makes just his second start against San Diego, taking a no-decision after 6 2/3 innings in July 2016.