Guardians vs. Athletics Prediction, Odds, Picks - April 21

Updated Apr. 21, 2024 1:00 p.m. ET

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Steven Kwan and the Cleveland Guardians will take the field at Progressive Field against the Oakland Athletics and Abraham Toro on Sunday. The favored Guardians have -171 moneyline odds to win against the underdog Athletics, who are listed at +143. Cleveland is the favorite on the run line (-1.5). The total is 7.5 runs for the game.

Here is everything you need from a betting perspective on the Guardians-Athletics game, regarding the run line, moneyline and total, plus expert picks.

Oakland Athletics vs. Cleveland Guardians Highlights | MLB on FOX

Check out the best plays and moments from the Cleveland Guardians' 10-2 win over the Oakland Athletics.

Guardians vs. Athletics Game Information & Odds

• When: Sunday, April 21, 2024 at 1:40 PM ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL

Guardians vs. Athletics Prediction

• Score Prediction: Guardians 5, Athletics 3
• Total Prediction: Over 7.5 runs
• Win Probabilities: Guardians 62%, Athletics 38%

Guardians vs. Athletics Betting Insights

• This season, the Guardians have been favored 12 times and won eight, or 66.7%, of those games.
• Cleveland has a record of 3-1 in games when sportsbooks favor them by at least -171 on the moneyline.
• The bookmakers' moneyline implies a 63.1% chance of a victory for the Guardians.
• The Athletics have won in six, or 31.6%, of the 19 contests they have been named as odds-on underdogs this year.
• This year, Oakland has won three of seven games when listed as at least +143 or worse on the moneyline.
• The Athletics have an implied victory probability of 41.2% according to the moneyline set by sportsbooks for this matchup.

FINAL

OAK 2 · CLE 6

MLB

RUN LINE

TO WIN

TOTAL

Oakland Athletics

OAK

+1.5

+142

o7.5

Cleveland Guardians

CLE

-1.5

-168

u7.5

Guardians Recent Betting Performance

• The Guardians went 4-1 across the five games they were moneyline favorites in their last 10 matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Guardians and their opponents combined to go over the run total seven times.
• The Guardians have put together a 6-4-0 record against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Josh Naylor's six homers in 2024 are the most on the Guardians. He's also knocked in 17 runs while hitting .329.
• Of all batters in MLB, Naylor ranks fourth in home runs and 13th in RBI.
• Naylor takes a hitting streak of eight games into this matchup. During his last 10 outings he is batting .342 with two doubles, four home runs, four walks and 10 RBI.
• Steven Kwan has a club-high .374 batting average.
• Including all MLB batters, Kwan is 101st in home runs and 151st in RBI.
• Kwan heads into this matchup looking for his third game in a row with a hit. In his last five games he is batting .391 with three doubles, a walk and two RBI.
• Jose Ramirez paces the Guardians with 18 runs batted in.
• Ramirez will look to build on his two-game hitting in this game. During his last five outings he is batting .211 with a double, a walk and five RBI.
• Andres Gimenez is batting .278 with five doubles, a triple and four walks.
• Gimenez has recorded at least one hit in two games in a row. In his last five games he is batting .238 with a walk and five RBI.

Guardians Team Props

Learn more about this Guardians vs. Athletics matchup on Fox Sports.

Athletics Recent Betting Performance

• In eight games as underdogs over the last 10 matchups, the Athletics have a record of 2-6.
• In their last 10 games with a total, the Athletics and their opponents are 4-6-0 when it comes to hitting the over.
• The Athletics have three wins against the spread in their last 10 chances.

Athletics Recent Stats

Athletics Player Insights

• Abraham Toro leads the team in batting average with a high-water mark of .254.
• Among all hitters in the majors, Toro-Hernandez is 101st in home runs and 120th in RBI.
• Toro-Hernandez takes a hitting streak of three games into this game. During his last five outings he is batting .211 with a double, a triple, a home run, a walk and two RBI.
• Shea Langeliers been a consistent power bat this season, as he leads his team with four home runs and 10 runs batted in.
• Langeliers ranks 31st in home runs and 86th in RBI among all MLB hitters this season.
• Esteury Ruiz has a double, a triple, two home runs and a walk while batting .375.
• Zachary Gelof is batting .188 with two doubles, a triple, two home runs and seven walks.

Athletics Team Props

Oakland Athletics vs. Cleveland Guardians Highlights | MLB on FOX

Check out the best plays and moments from the Cleveland Guardians' 10-2 win over the Oakland Athletics.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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MLB - Oakland Athletics vs. Cleveland Guardians - 04/21/2024