How to Watch Twins vs. Guardians: TV Channel & Live Stream - May 21

Updated May. 21, 2025 9:22 a.m. ET

Data Skrive

The Minnesota Twins and Cleveland Guardians meet on Wednesday at 1:10 p.m. ET. Trevor Larnach and Jose Ramirez have been on a tear in recent games for their respective squads.

Check out everything you need to know to watch the Twins vs. Guardians game.

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Twins vs. Guardians Game Information & How to Watch

Date	Favorite	Spread	Total	Favorite Moneyline	Underdog Moneyline	Result
5/1/2025	Twins	-1.5	9	-128	+109	4-3 CLE
4/30/2025	Twins	-1.5	7	-113	-106	4-2 CLE
4/29/2025	Guardians	-1.5	8	-131	+111	2-1 CLE
4/28/2025	Guardians	-1.5	8	-125	+106	11-1 MIN
9/19/2024	Twins	-1.5	8	-113	-107	3-2 CLE
9/18/2024	Guardians	-1.5	7	-132	+112	5-4 CLE
9/17/2024	Guardians	-1.5	8	-138	+117	4-1 MIN
9/16/2024	Twins	-1.5	7.5	-118	-101	4-3 CLE
8/11/2024	Twins	-1.5	8	-120	+100	5-3 CLE
8/10/2024	Twins	-1.5	8.5	-114	-105	2-1 CLE

Larnach has six doubles, a triple, seven home runs and 19 walks while batting .250.
In all of MLB, Larnach ranks 63rd in home runs and 74th in RBI.
Larnach carries a three-game hitting streak into this matchup. During his last five outings he is hitting .238 with a double, a triple, a home run, two walks and two RBIs.
Ty France is hitting .253 with eight doubles, three home runs and 10 walks.
France is 177th in home runs and 74th in RBI among all hitters in the majors.
Harrison Bader has six doubles, four home runs and 12 walks while hitting .280.
Ryan Jeffers is hitting .268 with nine doubles, three home runs and 13 walks.
Jeffers takes a three-game streak with at least one hit into this one. In his last five games he is batting .364 with a double, a home run, a walk and an RBI.

Date	Opponent	Score	Pitching Matchup
May 14	@ Orioles	W 8-6	Simeon Woods Richardson vs Cade Povich
May 15	@ Orioles	W 4-0	Chris Paddack vs Tomoyuki Sugano
May 16	@ Brewers	W 3-0	Joe Ryan vs Chad Patrick
May 17	@ Brewers	W 7-0	Pablo Lopez vs Tobias Myers
May 18	@ Brewers	L 5-2	Zebby Matthews vs Freddy Peralta
May 21	Guardians	-	Bailey Ober vs Logan Allen
May 21	Guardians	-	Chris Paddack vs Gavin Williams
May 23	Royals	-	Pablo Lopez vs Noah Cameron
May 24	Royals	-	Zebby Matthews vs Michael Wacha
May 25	Royals	-	Bailey Ober vs Kris Bubic
May 26	@ Rays	-	Joe Ryan vs Zack Littell

Ramirez is hitting .296 with nine doubles, nine home runs and 16 walks, while getting on base at a rate of .359.
Among all hitters in the big leagues, Ramirez is 32nd in home runs and 74th in RBI.
Ramirez has collected a hit in 12 games in a row. During his last 10 games he is batting .378 with two doubles, four home runs, four walks and seven RBIs.
Steven Kwan is hitting .311 to lead the lineup.
Kwan ranks 145th overall in home runs and 144th in RBI this year.
Kyle Manzardo has been solid source of run production for the Guardians with 10 long balls and 25 runs batted in.
Carlos Santana is hitting .222 with three doubles, four home runs and 23 walks.

Date	Opponent	Score	Pitching Matchup
May 13	Brewers	W 2-0	Logan Allen vs Quinn Priester
May 14	Brewers	L 9-5	Gavin Williams vs Logan Henderson
May 16	@ Reds	L 5-4	Tanner Bibee vs Brady Singer
May 17	@ Reds	L 4-1	Slade Cecconi vs Brent Suter
May 18	@ Reds	L 3-1	Luis Ortiz vs Andrew Abbott
May 21	@ Twins	-	Logan Allen vs Bailey Ober
May 21	@ Twins	-	Gavin Williams vs Chris Paddack
May 22	@ Tigers	-	Slade Cecconi vs Jack Flaherty
May 23	@ Tigers	-	Luis Ortiz vs Jackson Jobe
May 24	@ Tigers	-	Logan Allen vs Keider Montero
May 25	@ Tigers	-	Tanner Bibee vs Tarik Skubal