A look at what's happening all around the majors today:
Jacob deGrom, who carries a 3-0 record and 1.02 ERA into his start at San Diego, often has no-hit stuff. So Mets manager Terry Collins realizes he could find himself in a similar situation to Miami's Don Mattingly and the Dodgers' Dave Roberts, who each has removed a young pitcher in the middle of a no-hit bid because of a high pitch count this season. ''There's a big picture involved here,'' Collins said Wednesday. ''The big picture right now with us, with the expectations that are with this club, is to make sure they stay healthy.''
The Chicago Cubs open a four-game series against NL East-leading Washington at Wrigley Field with Kyle Hendricks (1-2) pitching on eight days' rest against Joe Ross (3-0). The Cubs are a major league-best 20-6.
San Francisco's Matt Cain takes an 0-3 record and a 7.00 ERA into his start against the Colorado Rockies in the opener of a homestand for the Giants.
Seattle left-hander Wade Miley (2-2, 5.06 ERA), coming off his first career shutout in a five-hitter against Kansas City, starts for the Mariners at the Houston Astros.