UTSA vs. Charlotte Prediction, Odds, Picks - November 15, 2025

Updated Nov. 15, 2025 9:04 a.m. ET

FOX Sports

The UTSA Roadrunners (4-5) visit the Charlotte 49ers (1-8) on Saturday, November 15, 2025 in a matchup between AAC foes at Jerry Richardson Stadium. Charlotte is a 17.5-point underdog. The over/under is set at 58.5.

Against the South Florida Bulls in their most recent contest, the Roadrunners lost 55-23. In their last game, the 49ers lost against the East Carolina Pirates, 48-22.

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UTSA vs. Charlotte Game Information & Odds

When: Saturday, November 15, 2025 at 12 p.m. ET
Location: Jerry Richardson Stadium in Charlotte, North Carolina
TV: ESPN+
Live Box Score on FOX Sports

UTSA vs Charlotte Betting Information updated as of November 15, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
UTSA	-17.5 (-104)	-826	+564	58.5	-106	-114

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UTSA vs. Charlotte Prediction

Pick ATS: UTSA (-17.5)
Pick OU: Over (58.5)
Prediction: UTSA 40, Charlotte 19

Predictions are made by the Data Skrive betting model.

Learn more about the UTSA Roadrunners vs. the Charlotte 49ers game on FOX Sports!

UTSA vs. Charlotte Betting Insights

Based on the spread and over/under, the implied score for the tilt is Roadrunners 38, 49ers 20.
The Roadrunners have an 89.2% chance to win this meeting based on the moneyline's implied probability. The 49ers hold a 15.1% implied probability.
UTSA has compiled a 4-5-0 ATS record so far this year.
Charlotte has won three games against the spread this season, failing to cover or pushing six times.

UTSA vs. Charlotte: 2025 Stats Comparison

	UTSA	Charlotte
Off. Points per Game (Rank)	32.8 (47)	18 (128)
Def. Points per Game (Rank)	33 (117)	38.4 (133)
Turnovers Allowed (Rank)	9 (23)	18 (127)
Turnovers Forced (Rank)	12 (59)	9 (100)

UTSA 2025 Key Players

Name	Position	Stats
Robert Henry	RB	982 YDS / 9 TD / 109.1 YPG / 7.6 YPC 17 REC / 112 REC YDS / 2 REC TD / 14 REC YPG
Owen McCown	QB	1,875 YDS (67.5%) / 18 TD / 5 INT
Devin McCuin	WR	45 REC / 467 YDS / 6 TD / 51.9 YPG
Will Henderson III	RB	418 YDS / 3 TD / 46.4 YPG / 6.2 YPC 13 REC / 87 REC YDS / 1 REC TD / 12.4 REC YPG
Shadrach Banks	LB	54 TKL / 4 TFL / 1 SACK / 2 INT
Nnanna Anyanwu	LB	18 TKL / 7 TFL / 5 SACK
Jimmy Wyrick	DB	38 TKL / 0 TFL
Kendrick Blackshire	LB	34 TKL / 1 TFL / 1 SACK / 1 INT

Charlotte 2025 Key Players

Name	Position	Stats
Javen Nicholas	WR	44 REC / 631 YDS / 5 TD / 70.1 YPG
E. Jai Mason	WR	26 REC / 350 YDS / 4 TD / 50 YPG
Conner Harrell	QB	737 YDS (66.7%) / 4 TD / 2 INT 67 RUSH YDS / 2 RUSH TD / 16.8 RUSH YPG
Grayson Loftis	QB	1,045 YDS (53.2%) / 8 TD / 5 INT
Reid Williford	LB	56 TKL / 4 TFL / 4 SACK
Shay Taylor	LB	46 TKL / 4 TFL / 2 SACK
Kadin Schmitz	LB	49 TKL / 0 TFL / 1 INT / 1 PD
Ja'Qurious Conley	DB	40 TKL / 0 TFL / 1 INT / 1 PD