2025 San Francisco 49ers Depth Chart Heading into NFL Week 1

The San Francisco 49ers enter the 2025 season as one of the league’s top contenders, returning a loaded roster on both sides of the ball. As they chase another NFC title, here’s how the depth chart is shaping up heading into NFL Week 1.

San Francisco 49ers 2025 Depth Chart

Offense

• QB: Brock Purdy, Mac Jones
• RB: Christian McCaffrey, Brian Robinson, Isaac Guerendo, Jordan James
• FB: Kyle Juszczyk
• WR: Jauan Jennings, Skyy Moore
• LWR: Jordan Watkins, Marquez Valdes-Scantling
• RWR: Ricky Pearsall
• TE: George Kittle, Luke Farrell, Jake Tonges
• LT: Trent Williams, Spencer Burford
• LG: Ben Bartch, Drew Moss
• C: Jake Brendel, Matt Hennessy
• RG: Dominick Puni, Connor Colby
• RT: Colton McKivitz, Austen Pleasants

Can Brock Purdy lead the 49ers back to the Super Bowl? | The Herd

San Francisco 49ers QB Brock Purdy said he was "trying to do too much" last season. Jason McIntyre says that the 49ers will be "Really good" this season due to their schedule, and asks if Purdy can lead them back to the Super Bowl.

Defense

• LDE: Nick Bosa, Yetur Gross-Matos, Robert Beal
• DT: Kalia Davis, Alfred Collins
• NT: Jordan Elliott, C.J. West, Jordan Jefferson
• RDE: Mykel Williams, Bryce Huff, Sam Okuayinonu
• WLB: Dee Winters, Nick Martin
• MLB: Fred Warner, Luke Gifford, Tatum Bethune
• NB: Upton Stout, Chase Lucas
• LCB: Renardo Green, Darrell Luter
• SS: Jason Pinnock
• FS: Marques Sigle, Ji’Ayir Brown
• RCB: Deommodore Lenoir, Siran Neal

Special Teams

• K: Jake Moody
• KR: Isaac Guerendo, Skyy Moore
• PR: Skyy Moore, Jordan Watkins, Ricky Pearsall
• LS: Jon Weeks

How to watch 49ers vs. Seahawks in Week 1

• Date: Sunday, September 7
• Time: 4:05 p.m. ET
• TV: FOX
• Streaming: FOXSports.com, FOX Sports App, FOX One (Try free for 7 days)