Astros vs. Orioles Prediction, Odds, Picks - August 15

The Baltimore Orioles and Gunnar Henderson hit the field against Carlos Correa and the Houston Astros on Friday at Daikin Park. The Orioles are listed as +120 moneyline underdogs in this matchup with the favorite Astros (-144). Houston is the favorite on the run line (-1.5 with +152 odds). The total for the contest has been set at 9 runs.

Here is everything you need to know from a betting perspective on the Astros-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Astros vs. Orioles Game Information & Odds

• When: Friday, August 15, 2025 at 8:10 p.m. ET
• Where: Daikin Park in Houston, Texas
• How to watch on TV: SCHN and MASN2

Astros vs. Orioles Prediction

• Score Prediction: Astros 4, Orioles 3
• Total Prediction: Under 9 runs
• Win Probabilities: Astros 58%, Orioles 42%

Astros vs. Orioles Betting Insights

• The Astros have been favorites in 82 games this season and won 44 (53.7%) of those contests.
• Houston is 18-14 this season when entering a game favored by -144 or more on the moneyline.
• The moneyline for this contest implies a 59% chance of a victory for the Astros.
• The Orioles have been victorious in 28, or 45.2%, of the 62 contests they have been chosen as underdogs in this season.
• This season, Baltimore has come away with a win eight times in 23 chances when named as an underdog of at least +120 or worse on the moneyline.
• The Orioles have an implied victory probability of 45.5% according to the moneyline set for this matchup.

Astros Recent Betting Performance

• The Astros have a 2-3 record from the five games they were moneyline favorites over their last 10 matchups.
• Over their last 10 matchups, the Astros and their opponents combined to go over the total seven times (all 10 games had set totals).
• The Astros have a 6-4-0 record against the spread over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Jose Altuve leads the Astros with 21 homers on the year. He's also hitting .283 with 63 RBI.
• Altuve is 35th in home runs and 52nd in RBI among all hitters in MLB.
• Jeremy Pena's .318 batting average paces his team.
• Pena is 112th in homers in baseball, and 130th in RBI.
• Pena has three games in a row with at least one hit. During his last five outings he is batting .273 with two home runs, a walk and two RBIs.
• Yainer Diaz is batting .254 with 16 doubles, a triple, 17 home runs and 15 walks.
• Diaz will look to build on his two-game hitting in this game. During his last five outings he is hitting .250 with a home run and three RBIs.
• Christian Walker's 65 runs batted in are a team-high mark.

Astros Team Props

Orioles Recent Betting Performance

• The Orioles have played as underdogs in seven of their past 10 games and won three of those contests.
• In their last 10 games with a total, the Orioles and their opponents are 2-7-1 when it comes to hitting the over.
• The Orioles have six wins against the spread in their last 10 chances.

Orioles Recent Stats

Orioles Player Insights

• Henderson paces the Orioles in home runs (14), runs batted in (51) and has put up a team-best batting average of .283.
• Henderson is 100th in homers and 96th in RBI among all batters in the big leagues.
• Henderson carries a seven-game hitting streak into this matchup. In his last 10 outings he is hitting .265 with four doubles, a home run, three walks and five RBIs.
• Jackson Holliday has shown his power as he paces his team with 14 home runs.
• Holliday ranks 100th overall in home runs and 130th in RBI this season.
• Adley Rutschman is batting .232 with 16 doubles, a triple, nine home runs and 37 walks.
• Jordan Westburg has swatted a team-high 14 long balls.

Orioles Team Props

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