Guardians vs. Astros Prediction, Odds, Picks - June 8

The Cleveland Guardians and Steven Kwan will take the field against the Houston Astros and Isaac Paredes at Progressive Field on Sunday, with the first pitch at 1:40 p.m. ET. The Astros are listed as +120 moneyline underdogs in this matchup with the favorite Guardians (-142). Cleveland is a 1.5-run favorite (at +148 odds). A 7.5-run total has been set in the matchup.

Take a look at everything you need from a betting perspective on the Guardians-Astros game, regarding the run line, moneyline and total, plus expert picks.

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Astros vs. Guardians Highlights | MLB on FOX

Check out the best moments from the Houston Astros vs. Cleveland Guardians on June 7th, 2025.

Guardians vs. Astros Game Information & Odds

• When: Sunday, June 8, 2025 at 1:40 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: MLB Network, CLEG, and SCHN

Guardians vs. Astros Prediction

• Score Prediction: Guardians 5, Astros 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Guardians 51%, Astros 49%

Guardians vs. Astros Betting Insights

• The Guardians have been favorites in 22 games this season and won 14 (63.6%) of those contests.
• Cleveland has a record of 5-2 in games when oddsmakers favor them by at least -142 on the moneyline.
• The bookmakers' moneyline implies a 58.7% chance of a victory for the Guardians.
• The Astros have been underdogs in 20 games this season and have come away with the win 11 times (55%) in those contests.
• This year, Houston has won four of five games when listed as at least +120 or worse on the moneyline.
• The moneyline set for this matchup implies the Astros have a 45.5% chance of walking away with the win.

Guardians Recent Betting Performance

• The Guardians went 2-1 over the three games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings (all had set totals), the Guardians combined with their opponents to go over the run total four times.
• The Guardians have put together a 5-5-0 record against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Not only does Jose Ramirez lead the Guardians in hitting with his .333 average, he also is their premier power option with 12 home runs and 31 RBI.
• In all of MLB, Ramirez is 28th in home runs and 70th in RBI.
• Ramirez takes a hitting streak of seven games into this game. In his last 10 games he is hitting .436 with two doubles, three home runs, five walks and five RBIs.
• Kwan is batting .314 with 14 doubles, five home runs and 21 walks.
• Kwan is 153rd in homers and 155th in RBI among all batters in the majors.
• Carlos Santana is batting .255 with six doubles, seven home runs and 31 walks.
• Kyle Manzardo has six doubles, two triples, 11 home runs and 23 walks while batting .205.

Guardians Team Props

Astros Recent Betting Performance

• The Astros have been underdogs once in the past 10 games and won that contest.
• The Astros and their opponents have combined to hit the over four times in their last 10 games with a total.
• The Astros have five wins against the spread in their last 10 chances.

Astros Recent Stats

Astros Player Insights

• Jeremy Pena leads the Astros with a .321 batting average.
• Among all batters in MLB, Pena ranks 64th in homers and 63rd in RBI.
• Pena takes a hitting streak of 13 games into this matchup. In his last 10 games he is hitting .439 with four doubles, two home runs, two walks and five RBIs.
• Paredes has hit 14 home runs with 38 runs batted in, leading the team in both categories.
• Among all major league batters, Paredes ranks 14th in homers and 27th in RBI.
• Jose Altuve is hitting .261 with six doubles, nine home runs and 17 walks.
• Jake Meyers is hitting .287 with 11 doubles, a triple, three home runs and 19 walks.

Astros Team Props

Astros vs. Guardians Highlights | MLB on FOX

Check out the best moments from the Houston Astros vs. Cleveland Guardians on June 7th, 2025.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cleveland Guardians

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