Astros vs. Athletics Prediction, Odds, Picks - May 27

Brent Rooker and the Athletics will hit the field on Tuesday at Daikin Park against Hunter Brown, who is expected to start for the Houston Astros. First pitch is set for 8:10 p.m. ET. The Astros are listed as -239 moneyline favorites for this matchup against the Athletics (+196). The Astros are a 1.5-run favorite (at -110 odds). The total is 8 runs for this contest (with -115 odds on the over and -105 odds on the under).

Here is everything you need from a betting perspective on the Astros-Athletics game, regarding the run line, moneyline and total, plus expert picks.

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Astros vs. Athletics Game Information & Odds

• When: Tuesday, May 27, 2025 at 8:10 p.m. ET
• Where: Daikin Park in Houston, Texas
• How to watch on TV: SCHN and NBCS-CA

Astros vs. Athletics Prediction

• Score Prediction: Astros 4, Athletics 3
• Total Prediction: Under 8 runs
• Win Probabilities: Astros 61%, Athletics 39%

Astros vs. Athletics Betting Insights

• This season, the Astros have won 18 out of the 34 games, or 52.9%, in which they've been favored.
• The Astros have not entered a game this season with shorter moneyline odds than -239.
• Sportsbooks have implied with the moneyline set for this matchup that the Astros have a 70.5% chance to win.
• The Athletics have been underdogs in 36 games this season and have come away with the win 14 times (38.9%) in those contests.
• The Athletics have been listed as an underdog of +196 or more on two occasions this season and lost both games.
• The Athletics have an implied victory probability of 33.8% according to the moneyline set for this matchup.

Astros Recent Betting Performance

• The Astros played as the moneyline favorite in three of their last 10 games, and they went 1-2 in those matchups.
• Over their last 10 matchups (all had set totals), the Astros combined with their opponents to go over the run total three times.
• The Astros are 6-4-0 against the spread over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Isaac Paredes paces the Astros in home runs (11) and runs batted in (31).
• Of all hitters in baseball, Paredes' home run total ranks him 21st, and his RBI tally puts him 27th.
• Paredes has collected a hit in three games in a row. In his last five games he is hitting .364 with a double, three home runs and six RBIs.
• Jeremy Pena is hitting .295 with eight doubles, a triple, six home runs and 14 walks.
• Pena is 94th in home runs in MLB, and 77th in RBI.
• Pena enters this matchup looking for his third game in a row with a hit. In his last five games he is hitting .222 with a triple, a walk and two RBIs.
• Jose Altuve is batting .257 with six doubles, six home runs and 16 walks.
• Altuve has at least one base hit in four games in a row. In his last five games he is batting .400 with two home runs, two walks and four RBIs.
• Jake Meyers is batting .300 to pace his team.

Astros Team Props

Athletics Recent Betting Performance

• The Athletics have played as underdogs in six of their past 10 games and won one of those contests.
• In their last 10 games with a total, the Athletics and their opponents have failed to hit the over five times.
• The Athletics have a record of 4-6-0 ATS over their last 10 games.

Athletics Recent Stats

Athletics Player Insights

• Jacob Wilson leads the team in batting average with a high-water mark of .350.
• In all of the big leagues, Wilson is 94th in home runs and 54th in RBI.
• Rooker has a team-high 12 home runs.
• Rooker ranks 13th among all hitters in the majors in homers, and 73rd in RBI.
• Tyler Soderstrom has a team-best 31 runs batted in.
• Shea Langeliers has six doubles, nine home runs and 18 walks while hitting .241.

Athletics Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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