Oklahoma vs. Alabama Prediction, Odds, Picks - December 19, 2025

Updated Dec. 19, 2025 3:04 p.m. ET

Data Skrive

The College Football Playoff first round will see the Oklahoma Sooners (10-2) hosting the Alabama Crimson Tide (10-3) at 8 p.m. ET at Gaylord Family Oklahoma Memorial Stadium in Norman, Oklahoma. Oklahoma is favored in the matchup, by 1.5 points. The point total is 40.5.

In their last game, the Sooners won against the LSU Tigers, 17-13. The Crimson Tide's last contest was against the Georgia Bulldogs, and they lost by a score of 28-7.

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Oklahoma vs. Alabama Game Information & Odds

When: Friday, December 19, 2025 at 8 p.m. ET
Location: Gaylord Family Oklahoma Memorial Stadium in Norman, Oklahoma
TV: ABC
Streaming: FOX One + ESPN Bundle

Oklahoma vs Alabama Betting Information updated as of December 19, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Oklahoma	-1.5 (-107)	-114	-105	40.5	-110	-110

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Oklahoma vs. Alabama Prediction

Pick ATS: Oklahoma (-1.5)
Pick OU: Over (40.5)
Prediction: Oklahoma 24, Alabama 20

Predictions are made by the Data Skrive betting model.

Learn more about the Oklahoma Sooners vs. the Alabama Crimson Tide game on FOX Sports!

Oklahoma vs. Alabama Betting Insights

Based on the spread and over/under, the implied score for the tilt is Sooners 21, Crimson Tide 20.
The Sooners have a 53.3% chance to win this game per the moneyline's implied probability. The Crimson Tide have a 51.2% implied probability.
Oklahoma has won seven games against the spread this season, while failing to cover five times.
Alabama has covered eight times in 13 matchups with a spread this year.

Oklahoma vs. Alabama: Head-to-Head

Over their last two meetings, Oklahoma has totaled two wins versus Alabama.
The last two times the Sooners have played the Crimson Tide, they have put up a 2-0 record against the spread. The scoring has yet to go over the point total.
Alabama has been outpaced by 23 points in its last two tilts against Oklahoma.

Oklahoma vs. Alabama: 2025 Stats Comparison

	Oklahoma	Alabama
Off. Points per Game (Rank)	26.4 (82)	31.2 (28)
Def. Points per Game (Rank)	13.9 (7)	17.4 (16)
Turnovers Allowed (Rank)	15 (63)	12 (22)
Turnovers Forced (Rank)	13 (92)	19 (35)

Oklahoma 2025 Key Players

Name	Position	Stats
John Mateer	QB	2,578 YDS (62.1%) / 12 TD / 10 INT 416 RUSH YDS / 7 RUSH TD / 37.8 RUSH YPG
Isaiah Sategna	WR	65 REC / 948 YDS / 7 TD / 79 YPG
Xavier Robinson	RB	417 YDS / 4 TD / 46.3 YPG / 5.2 YPC 14 REC / 89 REC YDS / 1 REC TD / 11.1 REC YPG
Tory Blaylock	RB	446 YDS / 4 TD / 40.5 YPG / 4.1 YPC
Taylor Wein	DL	29 TKL / 10 TFL / 6 SACK / 1 INT
R Mason Thomas	DL	21 TKL / 5 TFL / 6.5 SACK
Kip Lewis	LB	51 TKL / 6 TFL / 3 SACK
Owen Heinecke	LB	42 TKL / 3 TFL / 2 SACK

Alabama 2025 Key Players

Name	Position	Stats
Ty Simpson	QB	3,268 YDS (64.3%) / 26 TD / 5 INT 98 RUSH YDS / 2 RUSH TD / 7.5 RUSH YPG
Germie Bernard	WR	57 REC / 762 YDS / 7 TD / 63.5 YPG
Isaiah Horton	WR	35 REC / 430 YDS / 8 TD / 35.8 YPG
Ryan Williams	WR	42 REC / 631 YDS / 4 TD / 57.4 YPG
Bray Hubbard	DB	53 TKL / 2 TFL / 1 SACK / 4 INT
Yhonzae Pierre	LB	36 TKL / 9 TFL / 6 SACK
Justin Jefferson	LB	58 TKL / 3 TFL / 2 SACK / 1 INT
Deontae Lawson	LB	53 TKL / 0 TFL