How to Watch Louisville vs. Virginia: Time, TV Channel, Live Stream – October 4, 2025

At 3:30 p.m. ET on Saturday, Isaac Brown and the Louisville Cardinals (4-0) take on the Virginia Cavaliers (4-1). Go to ESPN2 to see the Cardinals play the Cavaliers.

Keep up with college football all season on FOX Sports. Learn more about the Louisville Cardinals and the Virginia Cavaliers.

How to Watch Louisville vs. Virginia

• When: Saturday, October 4, 2025 at 3:30 p.m. ET
• Location: L&N Federal Credit Union Stadium in Louisville, Kentucky
• TV Channel: ESPN2
• Live Box Score: FOX Sports

Louisville vs. Virginia: Head to Head

• Against Virginia, Louisville has tallied three wins over the past three matchups.
• In those games, the Cavaliers have a 2-1 record ATS, while the two teams have gone over the total on two occasions.
• Virginia has put up 28 fewer points than Louisville in their past three games.

Louisville's 2025 Schedule

Louisville 2025 Stats & Insights

• Louisville has the 62nd-ranked offense this year (409.3 yards per game), and has been even more effective defensively, ranking 18th-best with just 268.3 yards allowed per game.
• Louisville owns the 29th-ranked offense this season in terms of passing yards (279 passing yards per game), and has been better on the other side of the ball, ranking 14th-best with just 150.8 passing yards allowed per game.
• The Cardinals own the 37th-ranked defense this year (18.8 points allowed per game), and they've been better on the other side of the ball, ranking 24th-best with 38.3 points per game.
• The Cardinals are putting up 130.3 rushing yards per game on offense (103rd in the FBS), and they rank 42nd defensively with 117.5 rushing yards allowed per game.
• Louisville ranks 41st in third-down conversion rate this season (45.3%), but has been thriving on the defensive side of the ball, ranking 18th-best in the FBS with a 28.3% third-down percentage allowed.
• The Cardinals rank 29th in college football with a +3 turnover margin after forcing 9 turnovers (10th in the FBS) and committing six (74th in the FBS).

Louisville 2025 Key Players

Virginia's 2025 Schedule

Virginia 2025 Stats & Insights

• Virginia's defense ranks 64th in the FBS with 353.6 total yards given up per contest, but it has been bolstered by its offense, which ranks fifth-best by posting 539.6 total yards per contest.
• Virginia's pass offense has been leading the way for the team, as it ranks 22nd-best in the FBS with 296.2 passing yards per game. In terms of defense, it is giving up 222.2 passing yards per game, which ranks 79th.
• The Cavaliers' offensive attack has been paving the way for the team, as they rank eighth-best in the FBS with 45.6 points per game. In terms of defense, they are allowing 23.2 points per game, which ranks 66th.
• The Cavaliers' rushing attack has been leading the charge for the team, as they rank 11th-best in the FBS with 243.4 rushing yards per contest. In terms of defense, they are surrendering 131.4 rushing yards per game, which ranks 56th.
• Things have been positive for Virginia on both offense and defense on third down, as it is putting up a 57% third-down conversion rate (10th-best) and allowing a 25.4% third-down rate (12th-best).
• The Cavaliers sport a 0 turnover margin this season, which ranks 68th in the FBS.

Virginia 2025 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox?

Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Louisville Cardinals

Virginia Cavaliers

College Football