Clemson vs. Boston College Prediction, Odds, Picks - October 11, 2025

Updated Oct. 11, 2025 3:04 p.m. ET

Data Skrive

The Clemson Tigers (2-3) visit the Boston College Eagles (1-4) on Saturday, October 11, 2025 in a matchup between ACC foes at Alumni Stadium (Chestnut Hill, MA). Boston College is a two-touchdown underdog. The over/under is set at 54.5 for the contest.

The Tigers won versus the North Carolina Tar Heels in their last game, 38-10. In their last contest, the Eagles lost versus the Pittsburgh Panthers, 48-7.

Keep up with college football all season on FOX Sports.

Clemson vs. Boston College Game Information & Odds

When: Saturday, October 11, 2025 at 7:30 p.m. ET
Location: Alumni Stadium (Chestnut Hill, MA) in Boston, Massachusetts
TV: ACC Network
Live Box Score on FOX Sports

Clemson vs Boston College Betting Information updated as of October 11, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Clemson	-14 (-110)	-617	+451	54.5	-110	-110

Clemson vs. Boston College Prediction

Pick ATS: Boston College (+14)
Pick OU: Under (54.5)
Prediction: Clemson 29, Boston College 22

Predictions are made by the Data Skrive betting model.

Learn more about the Clemson Tigers vs. the Boston College Eagles game on FOX Sports!

Clemson vs. Boston College Betting Insights

Based on the spread and over/under, the implied score for the matchup is Tigers 34, Eagles 20.
The Tigers have an 86.1% chance to collect the win in this contest based on the moneyline's implied probability. The Eagles hold an 18.1% implied probability.
Clemson has a record of just 1-4-0 against the spread this season.
Boston College has covered twice in five games with a spread this season.

Clemson vs. Boston College: Head-to-Head

Clemson holds a 2-0 record against Boston College in their last two matchups.
The two teams have never hit the over on the point total while sharing a split 1-1 record in their meetings against the spread.
Boston College has been outscored by 34 points in its last two tilts against Clemson.

Clemson vs. Boston College: 2025 Stats Comparison

	Clemson	Boston College
Off. Points per Game (Rank)	23.4 (106)	31.4 (64)
Def. Points per Game (Rank)	20.2 (36)	31.6 (103)
Turnovers Allowed (Rank)	8 (93)	9 (111)
Turnovers Forced (Rank)	5 (89)	3 (120)

Clemson 2025 Key Players

Name	Position	Stats
Cade Klubnik	QB	1,250 YDS (64.5%) / 10 TD / 4 INT 56 RUSH YDS / 1 RUSH TD / 11.2 RUSH YPG
Adam Randall	RB	368 YDS / 3 TD / 73.6 YPG / 5.7 YPC 17 REC / 154 REC YDS / 3 REC TD / 38.5 REC YPG
Bryant Wesco Jr.	WR	26 REC / 431 YDS / 5 TD / 86.2 YPG
T.J. Moore	WR	20 REC / 272 YDS / 1 TD / 54.4 YPG
Ronan Hanafin	DB	32 TKL / 0 TFL / 1 INT / 1 PD
Avieon Terrell	DB	24 TKL / 1 TFL / 1 SACK
Sammy Brown	LB	32 TKL / 3 TFL / 1 SACK
Wade Woodaz	LB	35 TKL / 2 TFL

Boston College 2025 Key Players

Name	Position	Stats
Turbo Richard	RB	331 YDS / 4 TD / 66.2 YPG / 5.2 YPC 17 REC / 165 REC YDS / 2 REC TD / 33 REC YPG
Dylan Lonergan	QB	1,277 YDS (67.4%) / 9 TD / 3 INT -31 RUSH YDS / 1 RUSH TD / -6.2 RUSH YPG
Reed Harris	WR	17 REC / 285 YDS / 2 TD / 57 YPG
Lewis Bond	WR	38 REC / 366 YDS / 0 TD / 73.2 YPG
Omar Thornton	DB	20 TKL / 3 TFL / 1 SACK / 1 INT
Owen McGowan	LB	13 TKL / 2 TFL / 1 SACK
Carter Davis	DB	15 TKL / 1 TFL / 1 SACK
KP Price	DB	21 TKL / 0 TFL