Bills vs. Jets 2025 Prediction, Odds, Picks - Jan 4

The Buffalo Bills (11-5) are solid favorites, expected to win by at least a touchdown (currently -7.5) over the New York Jets (3-13). The Jets have lost four games straight. The expected point total for the matchup is 37.5.

Keep up with the 2025 NFL season on FOX Sports.

Bills vs. Jets Odds & Betting Lines

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Bills vs. Jets Prediction & Pick

• Pick ATS: Bills (-7.5)
  
• Pick OU: Over (37.5)
  
• Prediction: Bills 36 - Jets 13

How to Watch Buffalo vs. New York

• Game date: Sunday, January 4, 2026
• Time: 4:25 p.m. ET
• Venue: Highmark Stadium
• Location: Orchard Park, New York
• TV:
• Live Boxscore: FOX Sports

Bills vs. Jets Recent Matchups

• In their past five head-to-head contests, Buffalo has taken down New York four times.
• New York has been outpaced by 69 points in its last five tilts versus Buffalo.

Buffalo Betting Info

• Buffalo is 7-9-0 against the spread this year.
• The Bills have been favored by 7.5 points or more six times this season, and covered the spread in one of those games.
• Buffalo has combined with its opponent to gone over the point total in 50% of its contests this year (eight times over 16 games with a set point total).
• When playing as moneyline favorites, the Bills have won 64.3% of the time (9-5).
• Looking at this contest's moneyline, the Bills' implied win probability is 79.8%.

Bills Stats

Buffalo's Key Players

Offense

• Josh Allen has 3,668 passing yards (10th in the NFL), 25 touchdowns (seventh in the NFL) and 10 interceptions this year. He has completed 69.3% of his passes, averaging 229.3 yards per game and 8.0 per attempt.
• In addition to his passing stats, Allen has 579 rushing yards (second on the Bills), with 14 rushing touchdowns.
• James Cook's rushing statline this season includes 1,606 yards (first in the NFL) and 12 TDs. He's averaging 100.4 yards per game and 5.2 per attempt (third in the NFL).
• He's also caught 33 passes (on 40 targets) for 291 receiving yards with two touchdowns. He's averaging 18.2 receiving yards and 2.1 catches per game.
• Khalil Shakir has four touchdown catches this season, and has 72 catches for 719 yards on 95 targets, while averaging 4.5 catches and 44.9 yards per game.
• Dalton Kincaid has 523 receiving yards and five touchdowns with 36 catches on 46 targets. He's averaging 3.3 receptions and 47.5 yards per game.

Defense

• On defense for the Bills, Cole Bishop has put up 85 tackles, 4.0 TFL, two sacks, and three interceptions in 2025.
• Greg Rousseau has 46 tackles, 6.0 TFL, and seven sacks this season.
• Joey Bosa has recorded 29 tackles, 9.0 TFL, and five sacks this year.
• Matt Milano has 3.5 sacks (third on the Bills) as well as 7.0 TFL and 67 tackles this year.

New York Betting Info

• New York is 8-8-0 against the spread this year.
• This year, the Jets have an ATS record of 3-2 in their five games as an underdog of 7.5 points or more.
• New York's games have finished with a final combined score above the over/under 10 times this season.
• The Jets have won three, or 21.4%, of the 14 games they've played as underdogs this season.
• The moneyline for this contest implies a 24.4% chance of a victory for the Jets.

Jets Stats

New York's Key Players

Offense

• Breece Hall has rushed for four touchdowns this year, and has racked up 1,065 total rushing yards (66.6 per game and 4.4 per attempt).
• Hall has also played a role the receiving game with 350 yards (21.9 per game) on 36 receptions (2.3 per game), while being targeted 48 times. He has one receiving touchdown.
• Tyrod Taylor has 779 passing yards, five touchdowns and five interceptions. His completion percentage is 59.7% and he averages 129.8 yards per game and 5.8 per attempt.
• Taylor also has one rushing touchdown and 143 rushing yards (fourth on the Jets).
• In 15 games played this season, Adonai Mitchell has 33 catches (2.2 receptions per game on 4.7 targets per game) for 453 yards and two receiving touchdowns.
• Isaiah Davis has 236 rushing yards (third on the Jets) and one rushing touchdown, while averaging 14.8 yards per game and 5.5 per attempt.
• Davis has also added 21 catches (1.3 per game) for 186 yards (11.6 per game), without a receiving touchdown. He has been on the receiving end of 28 targets.

Defense

• So far in 2025, Jamien Sherwood has put up 2.0 sacks to go with 8.0 TFL and 147 tackles over 16 games.
• Quincy Williams has 79 tackles, 8.0 TFL, and 3.5 sacks. He is third on the Jets in tackles.
• Malachi Moore has 3.0 TFL and 86 tackles.
• Brandon Stephens has totaled 4.0 TFL and 72 tackles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox?

Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Buffalo Bills

New York Jets