Pirates vs. Astros Prediction, Odds, Picks - June 3

Lance McCullers gets the nod on the mound for the Houston Astros against the Pittsburgh Pirates and Oneil Cruz on Tuesday at 6:40 p.m. ET. The Astros are +137 moneyline underdogs for this matchup against the favored Pirates (-163). Pittsburgh is the run-line favorite (-1.5). The over/under is 7 runs for the game (with -116 odds on the over and -105 odds on the under).

Take a look at everything you need to know from a betting perspective on the Pirates-Astros game, regarding the run line, moneyline and total, plus expert picks.

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Pirates vs. Padres Highlights | MLB on FOX

Check out the best moments between the Pittsburgh Pirates and the San Diego Padres!

Pirates vs. Astros Game Information & Odds

• When: Tuesday, June 3, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and SCHN

Pirates vs. Astros Prediction

• Score Prediction: Astros 4, Pirates 3
• Total Prediction: Over 7 runs
• Win Probabilities: Pirates 51%, Astros 49%

Pirates vs. Astros Betting Insights

• The Pirates have been favorites in 17 games this season and won six (35.3%) of those contests.
• Pittsburgh has played as favorites of -163 or more twice this season and split those games.
• The implied probability of a win from the Pirates, based on the moneyline, is 62%.
• The Astros have been chosen as underdogs in 19 games this year and have walked away with the win 10 times (52.6%) in those games.
• Houston has been listed as an underdog of +137 or more on two occasions this season and split those games.
• The Astros have an implied victory probability of 42.2% according to the moneyline set by sportsbooks for this matchup.

Pirates Recent Betting Performance

• Over the last 10 games, the Pirates have been named the moneyline favorite by bookmakers only one time, a game they won.
• Over their last 10 outings (all had set totals), the Pirates combined with their opponents to hit the over on the total six times.
• The Pirates' ATS record is 6-4-0 over their past 10 games.

Pirates Recent Stats

Pirates Player Insights

• Cruz has racked up a team-high 12 home runs.
• In all of Major League Baseball, Cruz ranks 22nd in home runs and 88th in RBI.
• Bryan Reynolds' 34 runs batted in lead his team.
• Reynolds is 89th in home runs and 32nd in RBI on the year.
• Reynolds carries a five-game streak with at least one hit into this contest. In his last five games he is batting .550 with two doubles, a triple, a home run, three walks and seven RBIs.
• Andrew McCutchen leads the Pirates with a .264 batting average.
• McCutchen has at least one base hit in three games in a row. During his last five outings he is batting .300 with a double, two home runs, two walks and four RBIs.
• Isiah Kiner-Falefa has nine doubles, a triple, a home run and nine walks while hitting .303.
• Kiner-Falefa takes a five-game streak with at least one hit into this one. During his last five outings he is hitting .421 with four doubles and five RBIs.

Pirates Team Props

Astros Recent Betting Performance

• In three games as an underdog over the last 10 matchups, Houston has a perfect record of 3-0.
• In their last 10 games with a total, the Astros and their opponents have failed to hit the over six times.
• Over their last 10 games, the Astros are 5-5-0 against the spread.

Astros Recent Stats

Astros Player Insights

• Jeremy Pena paces the Astros with a .309 batting average.
• Pena's home run total puts him 54th in the big leagues, and he is 63rd in RBI.
• Pena carries an eight-game hitting streak into this matchup. During his last 10 games he is batting .368 with a double, a triple, three home runs, three walks and seven RBIs.
• Isaac Paredes has hit 11 home runs with 32 RBI, leading the team in both categories.
• Paredes is 30th among all hitters in the big leagues in home runs, and 43rd in RBI.
• Jose Altuve is hitting .263 with six doubles, nine home runs and 16 walks.
• Jake Meyers has nine doubles, a triple, three home runs and 16 walks while hitting .292.

Astros Team Props

Pirates vs. Padres Highlights | MLB on FOX

Check out the best moments between the Pittsburgh Pirates and the San Diego Padres!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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