Guardians vs. Marlins Prediction, Odds, Picks - August 14

The Cleveland Guardians and Carlos Santana will square off against Xavier Edwards and the Miami Marlins at Progressive Field on Thursday, with the first pitch at 6:40 p.m. ET. The favored Guardians have -125 moneyline odds against the underdog Marlins, who are listed at +105. Cleveland is a 1.5-run favorite (at +172 odds). The total is 7.5 runs for the game.

Check out everything you need to know from a betting perspective on the Guardians-Marlins game, regarding the run line, moneyline and total, plus expert picks.

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Marlins vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Miami Marlins and the Cleveland Guardians.

Guardians vs. Marlins Game Information & Odds

• When: Thursday, August 14, 2025 at 6:40 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and FDSFL

Guardians vs. Marlins Prediction

• Score Prediction: Guardians 5, Marlins 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Guardians 53%, Marlins 47%

Guardians vs. Marlins Betting Insights

• This season, the Guardians have won 32 out of the 52 games, or 61.5%, in which they've been favored.
• Cleveland has a record of 25-11, a 69.4% win rate, when favored by -125 or more by bookmakers this season.
• The implied probability of a win from the Guardians, based on the moneyline, is 55.6%.
• The Marlins have been victorious in 49, or 48.5%, of the 101 contests they have been chosen as underdogs in this season.
• This year, Miami has won 40 of 81 games when listed as at least +105 or worse on the moneyline.
• The moneyline set for this matchup implies the Marlins have a 48.8% chance of coming away with a victory in the contest.

Guardians Recent Betting Performance

• The Guardians have a 4-3 record from the seven games they were favored on the moneyline over their last 10 matchups.
• Over their last 10 matchups (all had set totals), the Guardians combined with their opponents to hit the over on the total six times.
• The Guardians' ATS record is 5-5-0 over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Not only does Jose Ramirez lead the Guardians in hitting with his .294 average, he also is their premier power option with 25 home runs and 63 RBI.
• Ramirez's home runs put him 15th in MLB, and he ranks 51st in RBI.
• Ramirez carries a two-game hitting streak into this matchup. During his last five outings he is hitting .250 with two doubles, two home runs, a walk and two RBIs.
• Steven Kwan is hitting .275 with 21 doubles, a triple, 10 home runs and 41 walks.
• Kwan ranks 154th in home runs and 163rd in RBI among all batters in MLB.
• Santana is batting .227 with nine doubles, 11 home runs and 50 walks.
• Kyle Manzardo has 14 doubles, two triples, 21 home runs and 36 walks while batting .242.

Guardians Team Props

Marlins Recent Betting Performance

• In five games as underdogs over the last 10 matchups, the Marlins have a record of 1-4.
• In their last 10 games with a total, the Marlins and their opponents have failed to hit the over four times.
• Over their last 10 games, the Marlins are 4-6-0 against the spread.

Marlins Recent Stats

Marlins Player Insights

• Kyle Stowers has put up a team-high 25 home runs and has driven in 72 runs.
• Stowers' home run total puts him 15th in the big leagues, and he ranks 20th in RBI.
• Edwards' .303 batting average is a team-high mark.
• Edwards ranks 360th in home runs and 202nd in RBI among all major league batters this season.
• Otto Lopez is batting .241 with 16 doubles, 11 home runs and 38 walks.
• Agustin Ramirez is hitting .236 with 24 doubles, a triple, 17 home runs and 24 walks.

Marlins Team Props

Marlins vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Miami Marlins and the Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cleveland Guardians

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