Guardians vs. Athletics Prediction, Odds, Picks - July 18

Jose Ramirez and the Cleveland Guardians will see JP Sears at the rubber for the Athletics in the first game of a three-game series, Friday at 7:10 p.m. ET. Bookmakers list the Guardians as -129 moneyline favorites, while giving the underdog Athletics +108 moneyline odds. The Guardians are a 1.5-run favorite (at +157 odds). An 8-run total has been set for the matchup.

Here's everything you need to know from a betting perspective on the Guardians-Athletics game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. Athletics Game Information & Odds

• When: Friday, July 18, 2025 at 7:10 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and NBCS-CA

Guardians vs. Athletics Prediction

• Score Prediction: Guardians 4, Athletics 3
• Total Prediction: Under 8 runs
• Win Probabilities: Guardians 56%, Athletics 44%

Guardians vs. Athletics Betting Insights

• The Guardians have been favorites in 35 games this season and won 21 (60%) of those contests.
• The Guardians have a record of 13-5, a 72.2% win rate, when they're favored by -129 or more by oddsmakers this season.
• The Guardians have a 56.3% chance to win this game based on the implied probability of the moneyline.
• The Athletics have been victorious in 30, or 39%, of the 77 contests they have been chosen as underdogs in this season.
• This season, the Athletics have come away with a win 23 times in 65 chances when named as an underdog of at least +108 or longer on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Athletics have a 48.1% chance of pulling out a win.

Guardians Recent Betting Performance

• The Guardians have a 3-1 record from the four games they were moneyline favorites over their last 10 matchups.
• In their last 10 matchups -- all had a set run total -- the Guardians and their opponents combined to go over the total five times.
• The Guardians' ATS record is 7-3-0 over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Ramirez leads the Guardians in home runs (18), runs batted in (50) and has accumulated a team-high batting average of .295.
• Of all batters in MLB, Ramirez's home run total places him 26th, and his RBI tally ranks him 52nd.
• Steven Kwan is hitting .285 with 20 doubles, a triple, six home runs and 33 walks.
• Kwan is 201st in homers and 152nd in RBI on the year.
• Carlos Santana is batting .232 with seven doubles, 11 home runs and 43 walks.
• Kyle Manzardo is batting .217 with 11 doubles, two triples, 15 home runs and 28 walks.
• Manzardo is riding a three-game hitting streak into this one. During his last five outings he is batting .200 with two home runs, three walks and four RBIs.

Guardians Team Props

Athletics Recent Betting Performance

• The Athletics have played as underdogs in seven of their past 10 games and have gone 3-4 in those contests.
• In their last 10 games with a total, the Athletics and their opponents are 4-4-2 when it comes to hitting the over.
• The Athletics have seven wins against the spread in their last 10 chances.

Athletics Recent Stats

Athletics Player Insights

• Brent Rooker has swatted a team-leading 20 long balls.
• In all of MLB, Rooker is 17th in homers and 36th in RBI.
• Rooker has collected a hit in six games in a row. During his last 10 outings he is hitting .351 with four doubles, three home runs, five walks and nine RBIs.
• Jacob Wilson's .329 batting average leads his team.
• Wilson is 138th among all hitters in the big leagues in homers, and 85th in RBI.
• Tyler Soderstrom leads the Athletics with 56 runs batted in.
• Lawrence Butler is hitting .251 with 24 doubles, two triples, 13 home runs and 41 walks.

Athletics Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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