Cubs vs. Pirates Prediction, Odds, Picks - April 29

The Chicago Cubs versus Pittsburgh Pirates game on Tuesday at 6:40 p.m. ET will feature a pair of hot hitters in Pete Crow-Armstrong and Oneil Cruz. The Pirates are +130 moneyline underdogs for this matchup with the favored Cubs (-154). Chicago is the run-line favorite (-1.5). The over/under is 8.5 runs for this matchup (with -120 odds to hit the over and -101 odds on the under).

Here is everything you need from a betting perspective on the Cubs-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Pirates vs. Dodgers Highlights | MLB on FOX

Check out the best moments between the Pittsburgh Pirates and the Los Angeles Dodgers.

Cubs vs. Pirates Game Information & Odds

• When: Tuesday, April 29, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and MARQ

Cubs vs. Pirates Prediction

• Score Prediction: Cubs 4, Pirates 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Cubs 56%, Pirates 44%

Cubs vs. Pirates Betting Insights

• This season, the Cubs have won 10 out of the 14 games, or 71.4%, in which they've been favored.
• Chicago has entered five games this season favored by -154 or more and is 4-1 in those contests.
• The implied probability of a win from the Cubs, based on the moneyline, is 60.6%.
• The Pirates have been underdogs in 18 games this season and have come away with the win six times (33.3%) in those contests.
• This season, Pittsburgh has been victorious three times in 12 chances when named as an underdog of at least +130 or worse on the moneyline.
• The Pirates have an implied victory probability of 43.5% according to the moneyline set by sportsbooks for this matchup.

Cubs Recent Betting Performance

• The Cubs were the moneyline favorite in six of their last 10 games, and finished 4-2 in those matchups.
• In their last 10 outings -- all had a set run total -- the Cubs and their opponents combined to hit the over on the total five times.
• The Cubs are 4-6-0 against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker has accumulated a team-best batting average of .289, and paces the Cubs in home runs (seven) and runs batted in (25).
• Tucker is 13th in homers and fifth in RBI among all hitters in MLB.
• Crow-Armstrong has 10 doubles, a triple, five home runs and six walks while hitting .286.
• Among all major league batters, Crow-Armstrong is 39th in homers and 22nd in RBI.
• Carson Kelly has a double, a triple, six home runs and 15 walks while batting .341.
• Ian Happ is hitting .260 with seven doubles, two home runs and 18 walks.

Cubs Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs in seven of their past 10 games and won three of those contests.
• The Pirates and their opponents have combined to hit the over five times in their last 10 games with a total.
• The Pirates have a record of 5-5-0 ATS over their last 10 games.

Pirates Recent Stats

Pirates Player Insights

• Cruz has a team-high eight home runs and has driven in 16 runs.
• In all of the big leagues, Cruz ranks eighth in homers and 40th in RBI.
• Andrew McCutchen has four doubles, three home runs and 11 walks while batting .276.
• McCutchen ranks 101st overall in homers and 144th in RBI this year.
• Enmanuel Valdez has three doubles, two triples, two home runs and 10 walks while batting .219.
• Ke'Bryan Hayes is batting .235 with two doubles, a triple, a home run and eight walks.

Pirates Team Props

Pirates vs. Dodgers Highlights | MLB on FOX

Check out the best moments between the Pittsburgh Pirates and the Los Angeles Dodgers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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