Blue Jays vs. Rays Prediction, Odds, Picks - September 17

Vladimir Guerrero Jr. and Junior Caminero are the hottest hitters on the Toronto Blue Jays and Tampa Bay Rays, who play on Wednesday at George M. Steinbrenner Field, at 7:05 p.m. ET. The Blue Jays are the favorite in this one, at -131, while the underdog Rays have +110 odds to win. Toronto (-1.5) is the favorite on the run line. The over/under is 7.5 runs for this game (with +102 odds on the over and -122 odds on the under).

Check out everything you need from a betting perspective on the Blue Jays-Rays game, regarding the run line, moneyline and total, plus expert picks.

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Blue Jays vs. Rays Game Information & Odds

• When: Wednesday, September 17, 2025 at 7:05 p.m. ET
• Where: George M. Steinbrenner Field in Tampa, Florida
• How to watch on TV: FDSSUN and SNET

Blue Jays vs. Rays Prediction

• Score Prediction: Rays 5, Blue Jays 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Blue Jays 51%, Rays 49%

Blue Jays vs. Rays Betting Insights

• The Blue Jays have been favorites in 76 games this season and won 46 (60.5%) of those contests.
• Toronto is 36-17 this season when entering a game favored by -131 or more on the moneyline.
• The bookmakers' moneyline implies a 56.7% chance of a victory for the Blue Jays.
• The Rays have been victorious in 29, or 39.7%, of the 73 contests they have been chosen as underdogs in this season.
• This season, Tampa Bay has been victorious 16 times in 37 chances when named as an underdog of at least +110 or worse on the moneyline.
• The moneyline set for this matchup implies the Rays have a 47.6% chance of coming away with a victory in the contest.

Blue Jays Recent Betting Performance

• The Blue Jays were the moneyline favorite in seven of their last 10 games, and finished 6-1 in those matchups.
• Over their last 10 outings, the Blue Jays and their opponents combined to hit the over on the run total three times (all 10 games had set totals).
• The Blue Jays have gone 4-6-0 against the spread over their past 10 games.

Blue Jays Recent Stats

Blue Jays Player Insights

• Guerrero is batting .302 with 33 doubles, 23 home runs and 80 walks.
• Guerrero is 52nd in homers and 36th in RBI among all batters in MLB.
• George Springer has shown his power as he leads his team with 29 home runs.
• Springer ranks 21st in home runs and 47th in RBI on the season.
• Springer has six games in a row with at least one hit. During his last 10 games he is hitting .317 with three doubles, two home runs, four walks and six RBIs.
• Ernie Clement has 31 doubles, two triples, nine home runs and 25 walks while batting .277.
• Alejandro Kirk is hitting .291 with 17 doubles, 12 home runs and 45 walks.

Blue Jays Team Props

Rays Recent Betting Performance

• The Rays have played as underdogs three times over their past 10 games and lost each of those contests.
• When it comes to hitting the over, the Rays and their opponents are 5-4-1 in their last 10 games with a total.
• The Rays are 3-7-0 ATS over their last 10 games.

Rays Recent Stats

Rays Player Insights

• Caminero leads the Rays with 44 home runs and runs batted in, driving in 108.
• Caminero's home run total places him sixth in the big leagues, and he is fifth in RBI.
• Yandy Diaz's .296 batting average paces his team.
• Diaz is currently 47th in homers and 39th in RBI in the big leagues.
• Brandon Lowe is batting .258 with 18 doubles, 29 home runs and 36 walks.
• Chandler Simpson has 11 doubles, three triples and 20 walks while batting .291.

Rays Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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