Washington vs. UCLA Prediction, Odds, Picks - November 22, 2025

Updated Nov. 22, 2025 9:04 p.m. ET

Data Skrive

Big Ten rivals meet when the Washington Huskies (7-3) visit the UCLA Bruins (3-7) on Saturday, November 22, 2025 at the Rose Bowl. Washington is favored by 10.5 points. The point total is 51.5.

The Huskies won against the Purdue Boilermakers in their most recent game, 49-13. In their last game, the Bruins lost against the Ohio State Buckeyes, 48-10.

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Washington vs. UCLA Game Information & Odds

When: Saturday, November 22, 2025 at 10:30 p.m. ET
Location: Rose Bowl in Pasadena, California
TV: NBC
Live Box Score on FOX Sports

Washington vs UCLA Betting Information updated as of November 22, 2025, 12:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Washington	-10.5 (-114)	-427	+325	51.5	-106	-114

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Washington vs. UCLA Prediction

Pick ATS: Washington (-10.5)
Pick OU: Under (51.5)
Prediction: Washington 31, UCLA 20

Predictions are made by the Data Skrive betting model.

Learn more about the Washington Huskies vs. the UCLA Bruins game on FOX Sports!

Washington vs. UCLA Betting Insights

Based on the spread and over/under, the implied score for the matchup is Huskies 31, Bruins 20.
The Huskies have an 81.0% chance to collect the win in this meeting based on the moneyline's implied probability. The Bruins hold a 23.5% implied probability.
Washington has compiled a 4-5-0 ATS record so far this year.
UCLA has covered three times in 10 games with a spread this season.

Washington vs. UCLA: Head-to-Head

UCLA owns a 2-1 record against Washington in their last three matchups.
The last three times the Bruins have played the Huskies, they have put up a 2-1 record against the spread. The scoring has gone over the point total on two occasions.
In their last three head-to-head matchups, UCLA has scored 83 points versus Washington, while allowing only 80 points.

Washington vs. UCLA: 2025 Stats Comparison

	Washington	UCLA
Off. Points per Game (Rank)	34.3 (38)	19.4 (124)
Def. Points per Game (Rank)	19.3 (17)	32.4 (111)
Turnovers Allowed (Rank)	9 (12)	10 (21)
Turnovers Forced (Rank)	11 (93)	8 (122)

Washington 2025 Key Players

Name	Position	Stats
Demond Williams Jr.	QB	2,508 YDS (72.6%) / 17 TD / 5 INT 513 RUSH YDS / 4 RUSH TD / 51.3 RUSH YPG
Jonah Coleman	RB	645 YDS / 13 TD / 71.7 YPG / 4.9 YPC 29 REC / 335 REC YDS / 2 REC TD / 37.2 REC YPG
Denzel Boston	WR	52 REC / 730 YDS / 8 TD / 81.1 YPG
Dezmen Roebuck	WR	32 REC / 431 YDS / 5 TD / 47.9 YPG
Alex McLaughlin	DB	66 TKL / 1 TFL / 2 INT / 2 PD
Makell Esteen	DB	42 TKL / 0 TFL / 0.5 SACK / 2 INT
Jacob Lane	DL	32 TKL / 5 TFL / 3.5 SACK
Deven Bryant	LB	50 TKL / 1 TFL

UCLA 2025 Key Players

Name	Position	Stats
Nico Iamaleava	QB	1,659 YDS (63.7%) / 12 TD / 7 INT 474 RUSH YDS / 4 RUSH TD / 47.4 RUSH YPG
Kwazi Gilmer	WR	37 REC / 432 YDS / 3 TD / 43.2 YPG
Jalen Berger	RB	281 YDS / 2 TD / 28.1 YPG / 4.1 YPC 8 REC / 64 REC YDS / 2 REC TD / 12.8 REC YPG
Anthony Woods	RB	252 YDS / 0 TD / 28 YPG / 4.8 YPC 17 REC / 166 REC YDS / 2 REC TD / 23.7 REC YPG
JonJon Vaughns	LB	85 TKL / 4 TFL
Key Lawrence	DB	55 TKL / 4 TFL / 1 INT / 1 PD
Isaiah Chisom	LB	67 TKL / 1 TFL
Cole Martin	DB	52 TKL / 3 TFL