UConn vs. Rice Prediction, Odds, Picks - October 25, 2025

Updated Oct. 25, 2025 3:04 p.m. ET

FOX Sports

The Rice Owls (3-4) will try to defy oddsmakers when they take on the UConn Huskies (5-2) on Saturday, October 25, 2025 as a 10.5-point underdog. A 48.5-point over/under is set for the contest.

In their most recent game, the Huskies won against the Boston College Eagles, 38-23. Last time out, the Owls fell to the UTSA Roadrunners, with 61-13 being the final score.

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UConn vs. Rice Game Information & Odds

When: Saturday, October 25, 2025 at 3 p.m. ET
Location: Rice Stadium in Houston, Texas
TV: ESPN+
Live Box Score on FOX Sports

UConn vs Rice Betting Information updated as of October 25, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
UConn	-10.5 (-109)	-388	+305	48.5	-107	-113

UConn vs. Rice Prediction

Pick ATS: UConn (-10.5)
Pick OU: Over (48.5)
Prediction: UConn 34, Rice 17

Predictions are made by the Data Skrive betting model.

Learn more about the UConn Huskies vs. the Rice Owls game on FOX Sports!

UConn vs. Rice Betting Insights

Per the spread and over/under, the implied score for the matchup is Huskies 30, Owls 19.
The Huskies have a 79.5% chance to claim victory in this meeting based on the moneyline's implied probability. The Owls have a 24.7% implied probability.
UConn is 3-2-2 ATS this season.
Rice has compiled a 3-4-0 ATS record so far this season.

UConn vs. Rice: Head-to-Head

UConn has a 2-0 record against Rice in their last two matchups.
The Huskies have a 2-0 record ATS in those games, while the two teams have gone over the total on one occasion.
Rice has been outpaced by 14 points in its last two tilts versus UConn.

UConn vs. Rice: 2025 Stats Comparison

	UConn	Rice
Off. Points per Game (Rank)	37.1 (18)	19.4 (121)
Def. Points per Game (Rank)	22.7 (57)	27.1 (89)
Turnovers Allowed (Rank)	1 (1)	4 (7)
Turnovers Forced (Rank)	8 (70)	6 (99)

UConn 2025 Key Players

Name	Position	Stats
Joe Fagnano	QB	1,918 YDS (68.1%) / 15 TD / 0 INT 94 RUSH YDS / 2 RUSH TD / 13.4 RUSH YPG
Cam Edwards	RB	694 YDS / 7 TD / 99.1 YPG / 6.1 YPC 6 REC / 66 REC YDS / 0 REC TD / 13.2 REC YPG
Skyler Bell	WR	58 REC / 687 YDS / 7 TD / 98.1 YPG
Reymello Murphy	WR	17 REC / 219 YDS / 3 TD / 36.5 YPG
Bryun Parham	LB	54 TKL / 7 TFL / 8.5 SACK
Oumar Diomande	LB	49 TKL / 4 TFL / 3 SACK
Tyquan King	LB	27 TKL / 3 TFL / 3 SACK
Cam Chadwick	DB	34 TKL / 0 TFL / 1 INT / 2 PD

Rice 2025 Key Players

Name	Position	Stats
Chase Jenkins	QB	553 YDS (67.4%) / 4 TD / 1 INT 275 RUSH YDS / 4 RUSH TD / 39.3 RUSH YPG
Quinton Jackson	RB	487 YDS / 3 TD / 69.6 YPG / 5.1 YPC
Daelen Alexander	RB	370 YDS / 3 TD / 52.9 YPG / 5.9 YPC
Drayden Dickmann	WR	24 REC / 262 YDS / 3 TD / 37.4 YPG
Ty Anthony Morris	LB	24 TKL / 4 TFL / 2 SACK
Tony Anyanwu	DL	19 TKL / 2 TFL / 3 SACK
Andrew Awe	LB	35 TKL / 2 TFL / 0.5 SACK
Michael Daley	DL	8 TKL / 4 TFL / 4.5 SACK