South Florida vs. UTSA Prediction, Odds, Picks - November 6, 2025

Updated Nov. 6, 2025 3:05 p.m. ET

FOX Sports

The South Florida Bulls (6-2) are 13.5-point favorites when they host the UTSA Roadrunners (4-4) in an AAC matchup on Thursday, November 6, 2025 at Raymond James Stadium. The game's point total is set at 67.5.

Last time around, the Bulls fell to the Memphis Tigers, with 34-31 being the final score. In their last game, the Roadrunners won against the Tulane Green Wave, 48-26.

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South Florida vs. UTSA Game Information & Odds

When: Thursday, November 6, 2025 at 7:30 p.m. ET
Location: Raymond James Stadium in Tampa, Florida
TV: ESPN
Live Box Score on FOX Sports

South Florida vs UTSA Betting Information updated as of November 6, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
South Florida	-13.5 (-122)	-599	+437	67.5	-112	-107

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South Florida vs. UTSA Prediction

Pick ATS: South Florida (-13.5)
Pick OU: Under (67.5)
Prediction: South Florida 40, UTSA 23

Predictions are made by the Data Skrive betting model.

Learn more about the South Florida Bulls vs. the UTSA Roadrunners game on FOX Sports!

South Florida vs. UTSA Betting Insights

Based on the spread and over/under, the implied score for the tilt is Bulls 40, Roadrunners 27.
The Bulls have an 85.7% chance to claim victory in this meeting based on the moneyline's implied probability. The Roadrunners have an 18.6% implied probability.
South Florida is 5-2-1 ATS this season.
UTSA has put together a 4-4-0 record against the spread this season.

South Florida vs. UTSA: 2025 Stats Comparison

	South Florida	UTSA
Off. Points per Game (Rank)	40.4 (14)	34 (45)
Def. Points per Game (Rank)	24.4 (51)	30.3 (96)
Turnovers Allowed (Rank)	11 (72)	7 (14)
Turnovers Forced (Rank)	17 (9)	11 (52)

South Florida 2025 Key Players

Name	Position	Stats
Byrum Brown	QB	1,964 YDS (62.9%) / 17 TD / 6 INT 596 RUSH YDS / 8 RUSH TD / 74.5 RUSH YPG
Chas Nimrod	WR	23 REC / 466 YDS / 3 TD / 77.7 YPG
Jeremiah Koger	WR	17 REC / 337 YDS / 5 TD / 56.2 YPG
Keshaun Singleton	WR	29 REC / 451 YDS / 3 TD / 56.4 YPG
Mac Harris	LB	68 TKL / 5 TFL / 5.5 SACK / 1 INT
Jhalyn Shuler	LB	64 TKL / 4 TFL / 1 SACK / 1 INT
Jarvis Lee Jr.	DB	35 TKL / 6 TFL / 1 SACK / 2 INT
Rico Watson	RB	30 TKL / 3 TFL / 2 SACK / 1 INT

UTSA 2025 Key Players

Name	Position	Stats
Robert Henry	RB	955 YDS / 9 TD / 119.4 YPG / 8 YPC 15 REC / 109 REC YDS / 2 REC TD / 15.6 REC YPG
Owen McCown	QB	1,675 YDS (67.3%) / 17 TD / 4 INT
Devin McCuin	WR	43 REC / 460 YDS / 6 TD / 57.5 YPG
Will Henderson III	RB	391 YDS / 3 TD / 48.9 YPG / 6.3 YPC 12 REC / 82 REC YDS / 1 REC TD / 13.7 REC YPG
Shadrach Banks	LB	54 TKL / 4 TFL / 1 SACK / 2 INT
Nnanna Anyanwu	LB	18 TKL / 7 TFL / 5 SACK
Jimmy Wyrick	DB	38 TKL / 0 TFL
Kendrick Blackshire	LB	34 TKL / 1 TFL / 1 SACK / 1 INT