SMU vs. Stanford Prediction, Odds, Picks - October 11, 2025

Updated Oct. 11, 2025 9:04 a.m. ET

FOX Sports

ACC rivals meet when the SMU Mustangs (3-2) host the Stanford Cardinal (2-3) on Saturday, October 11, 2025 at Gerald J. Ford Stadium. SMU is favored by 19.5 points. The point total is set at 55.5 for the outing.

In their last game, the Mustangs won against the Syracuse Orange, 31-18. The Cardinal's most recent game was against the San Jose State Spartans, and they won by a score of 30-29.

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SMU vs. Stanford Game Information & Odds

When: Saturday, October 11, 2025 at 12 p.m. ET
Location: Gerald J. Ford Stadium in University Park, Texas
TV: The CW
Live Box Score on FOX Sports

SMU vs Stanford Betting Information updated as of October 11, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
SMU	-19.5 (-111)	-1149	+727	55.5	-104	-116

SMU vs. Stanford Prediction

Pick ATS: Stanford (+19.5)
Pick OU: Under (55.5)
Prediction: SMU 34, Stanford 21

Predictions are made by the Data Skrive betting model.

Learn more about the SMU Mustangs vs. the Stanford Cardinal game on FOX Sports!

SMU vs. Stanford Betting Insights

Based on the spread and over/under, the implied score for the tilt is Mustangs 38, Cardinal 18.
The Mustangs have a 92.0% chance to win this meeting based on the moneyline's implied probability. The Cardinal have a 12.1% implied probability.
SMU is winless against the spread this season (0-4-0).
Stanford has won just one game against the spread this year.

SMU vs. Stanford: 2025 Stats Comparison

	SMU	Stanford
Off. Points per Game (Rank)	34 (53)	20.6 (119)
Def. Points per Game (Rank)	24.8 (61)	29.4 (87)
Turnovers Allowed (Rank)	9 (111)	6 (54)
Turnovers Forced (Rank)	12 (6)	5 (89)

SMU 2025 Key Players

Name	Position	Stats
Kevin Jennings	QB	1,411 YDS (71.4%) / 13 TD / 6 INT 25 RUSH YDS / 1 RUSH TD / 5 RUSH YPG
Tomarion Harden	RB	375 YDS / 5 TD / 75 YPG / 5.1 YPC 5 REC / 24 REC YDS / 0 REC TD / 12 REC YPG
Romello Brinson	WR	26 REC / 436 YDS / 3 TD / 87.2 YPG
Jalen Cooper	WR	15 REC / 271 YDS / 2 TD / 54.2 YPG
Cam Robertson	DL	20 TKL / 4 TFL / 3 SACK
Ahmaad Moses	DB	26 TKL / 2 TFL / 1 SACK / 2 INT
Isaiah Nwokobia	DB	25 TKL / 0 TFL / 1 INT / 1 PD
Jeffrey M'ba	DL	12 TKL / 3 TFL / 3 SACK

Stanford 2025 Key Players

Name	Position	Stats
Micah Ford	RB	347 YDS / 3 TD / 69.4 YPG / 4.6 YPC 8 REC / 77 REC YDS / 0 REC TD / 15.4 REC YPG
Ben Gulbranson	QB	1,167 YDS (60.3%) / 5 TD / 3 INT
Bryce Farrell	WR	18 REC / 346 YDS / 1 TD / 86.5 YPG
CJ Williams	WR	28 REC / 295 YDS / 0 TD / 59 YPG
Matt Rose	LB	29 TKL / 3 TFL / 1 SACK
Clay Patterson	DL	8 TKL / 2 TFL / 3 SACK
Hunter Barth	LB	12 TKL / 3 TFL / 2 SACK
Collin Wright	DB	15 TKL / 0 TFL / 1 INT / 1 PD