Missouri vs. Louisiana Prediction, Odds, Picks - September 13, 2025

Updated Sep. 13, 2025 9:04 a.m. ET

Data Skrive

The Louisiana Ragin' Cajuns (1-1) will attempt to prove oddsmakers wrong when they square off against the No. 25 Missouri Tigers (2-0) on Saturday, September 13, 2025 as an overwhelming 27-point underdog. The contest has an over/under of 47.5 points.

The Tigers won versus the Kansas Jayhawks in their last game, 42-31. The Ragin' Cajuns won versus the McNeese Cowboys in their last game, 34-10.

Keep up with college football all season on FOX Sports.

Missouri vs. Louisiana Game Information & Odds

When: Saturday, September 13, 2025 at 1 p.m. ET
Location: Memorial Stadium/Faurot Field in Columbia, Missouri
TV: SEC Network+
Live Box Score on FOX Sports

Missouri vs Louisiana Betting Information updated as of September 13, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Missouri	-27 (-110)	-5556	+1770	47.5	-110	-110

Missouri vs. Louisiana Prediction

Pick ATS: Louisiana (+27)
Pick OU: Over (47.5)
Prediction: Missouri 35, Louisiana 14

Predictions are made by the Data Skrive betting model.

Learn more about the Missouri Tigers vs. the Louisiana Ragin' Cajuns game on FOX Sports!

Missouri vs. Louisiana Betting Insights

Based on the spread and over/under, the implied score for the tilt is Tigers 37, Ragin' Cajuns 10.
The Tigers have a 98.2% chance to collect the win in this game per the moneyline's implied probability. The Ragin' Cajuns have a 5.3% implied probability.
Missouri has a record of 2-0-0 against the spread this season.
Louisiana has put together a 0-1-0 record against the spread this year.

Missouri vs. Louisiana: 2025 Stats Comparison

	Missouri	Louisiana
Off. Points per Game (Rank)	51.5 (17)	23 (97)
Def. Points per Game (Rank)	18.5 (60)	12 (35)
Turnovers Allowed (Rank)	1 (22)	2 (54)
Turnovers Forced (Rank)	3 (37)	2 (64)

Missouri 2025 Key Players

Name	Position	Stats
Beau Pribula	QB	617 YDS (79.1%) / 5 TD / 0 INT 71 RUSH YDS / 2 RUSH TD / 35.5 RUSH YPG
Ahmad Hardy	RB	212 YDS / 2 TD / 106 YPG / 6.1 YPC
Brett Norfleet	TE	10 REC / 85 YDS / 3 TD / 42.5 YPG
Jamal Roberts	RB	176 YDS / 1 TD / 88 YPG / 8.4 YPC
Zion Young	DL	5 TKL / 0 TFL / 1 SACK
Damon Wilson Jr.	DL	2 TKL / 2 TFL / 2 SACK
Josiah Trotter	LB	12 TKL / 2 TFL
Daylan Carnell	DB	6 TKL / 1 TFL / 1 INT / 1 PD

Louisiana 2025 Key Players

Name	Position	Stats
Elijah Davis	RB	190 YDS / 2 TD / 95 YPG / 6.3 YPC
Zylan Perry	RB	140 YDS / 0 TD / 70 YPG / 5.6 YPC
Steven Blanco	RB	69 YDS / 1 TD / 69 YPG / 11.5 YPC
Walker Howard	QB	88 YDS (45.5%) / 0 TD / 1 INT 47 RUSH YDS / 1 RUSH TD / 47 RUSH YPG
Terrence Williams	LB	8 TKL / 2 TFL / 1 SACK
Jaden Dugger	LB	10 TKL / 0 TFL
Jalen Clark	DB	5 TKL / 1 TFL / 1 INT / 1 PD
Caleb Kibodi	LB	4 TKL / 1 TFL / 1 SACK