Chargers vs. Texans 2025 Prediction, Odds, Picks - Dec 27

Updated Dec. 27, 2025 2:43 p.m. ET

Data Skrive

The Los Angeles Chargers (11-4) and Houston Texans (10-5) will meet, with both teams on win streaks -- the Chargers four in a row, the Texans seven in a row. Los Angeles is a slight favorite (-1.5). The total for this one is set at 40.5 points.

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Chargers vs. Texans Odds & Betting Lines

Chargers vs Texans Betting Information updated as of December 27, 2025, 2:33 p.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Chargers	-1.5	-108	-123	40.5	-115	-105

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Chargers vs. Texans Prediction & Pick

Pick ATS: Texans (+1.5)
Pick OU: Over (40.5)
Prediction: Texans 24 - Chargers 18

How to Watch Los Angeles vs. Houston

Game date: Saturday, December 27, 2025
Time: 4:30 p.m. ET
Venue: SoFi Stadium
Location: Inglewood, California
TV: NFL Network
Live Boxscore: FOX Sports

Chargers vs. Texans Recent Matchups

In their last four head-to-head matchups, Houston has taken down Los Angeles three times.
In their last four head-to-head matchups, Houston has compiled 124 points against Los Angeles, while allowing only 95 points.

Los Angeles Betting Info

In 15 Los Angeles games this year, it has nine wins against the spread.
The Chargers are 5-6 ATS this season when playing as at least 1.5-point favorites.
Los Angeles games this year have hit the over on six of 15 set point totals (40%).
When playing as the moneyline favorite, the Chargers have won 63.6% of the time (7-4).
Based on this contest's moneyline, the Chargers' implied win probability is 54.1%.

Chargers Stats

Stat	Average (Total)	Rank
Pass yards	220.2 (3,303)	13
Rush yards	125.3 (1,880)	6
Points scored	23.3 (349)	17
Pass yards against	179.3 (2,690)	6
Rush yards against	103.8 (1,557)	9
Points allowed	20.1 (301)	8

Los Angeles' Key Players

Offense

Justin Herbert has 3,491 passing yards (eighth in the NFL), 25 touchdowns (fifth in the NFL) and 12 interceptions this year. He has completed 66.5% of his passes, averaging 232.7 yards per game and 7.3 per attempt.
He has tacked on 461 rushing yards (30.7 per game) and two touchdowns on the ground.
Ladd McConkey has caught 65 passes on 104 targets for 758 total yards and six touchdowns. He is averaging 4.3 catches and 50.5 yards per game through 15 games.
In the passing attack, Quentin Johnston, has contributed with 637 receiving yards and eight touchdowns (eighth in the NFL) after grabbing 46 balls on 77 targets. Per game, he's averaging 53.1 yards and 3.8 receptions through 12 games.
Kimani Vidal has run for 631 yards, averaging 52.6 yards per game and scoring three touchdowns.
Vidal has been targeted 21 times to the tune of 15 receptions, 138 yards and one TD.

Defense

On defense for the Chargers, Tuli Tuipulotu has powered the unit with 43 tackles, 20.0 TFL, and 13 sacks in 2025.
Daiyan Henley has picked off two pases and added 90 tackles, 5.0 TFL, 3.5 sacks, and five passes defended.
Derwin James has totaled 86 tackles, 6.0 TFL, two sacks, and two interceptions this year.
Odafe Oweh has 7.0 sacks (second on the Chargers) to go along with his 9.0 TFL and 33 tackles on the year.

Houston Betting Info

Houston has gone 8-7-0 against the spread this year.
The Texans have been underdogs by 1.5 points or more seven times this year and are 4-3 ATS in those games.
Houston's games have finished with a final combined score above the over/under five times this year.
The Texans have entered the game as underdogs seven times this season and won four of those games.
The moneyline for this contest implies a 50.5% chance of a victory for the Texans.

Texans Stats

Stat	Average (Total)	Rank
Pass yards	217.2 (3,258)	16
Rush yards	106.7 (1,600)	23
Points scored	23.1 (346)	20
Pass yards against	176.1 (2,641)	4
Rush yards against	96.2 (1,443)	4
Points allowed	16.6 (249)	1

Houston's Key Players

Offense

C.J. Stroud is averaging 7.1 passing yards per attempt (16th in the NFL) and 219.0 yards per game this year, completing 65.3% of his passes on the way to 2,628 total yards, 16 touchdowns and six interceptions through 12 games.
Stroud has also rushed for 204 yards (third on the Texans).
Nico Collins has 68 catches for 1,060 yards (eighth in the NFL) and six receiving touchdowns. He has been targeted 116 times and averages 4.9 receptions per game through 14 games played.
Woody Marks has rushed for two touchdowns this year, and has totaled 584 rushing yards (41.7 per game and 3.5 per attempt).
Marks' statistic output includes 21 receptions (1.5 per game) on 31 targets for 204 yards (14.6 per game) and three receiving touchdowns.
Dalton Schultz has been targeted 98 times, resulting in 75 catches for 685 yards .

Defense

Will Anderson Jr. has 45 tackles, 17.0 TFL, 11.5 sacks, and three passes defended in 2025.
Danielle Hunter's stats include 48 tackles, 13.0 TFL, 13 sacks, and three passes defended.
In the 2025 campaign, Kamari Lassiter has 85 tackles, 7.0 TFL, and four interceptions through 15 games.
Azeez Al-Shaair's stats include one interception as well as 96 tackles, 1.0 TFL, and eight passes defended in 14 games

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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