Chargers vs. Texans 2025 Prediction, Odds, Picks - Dec 27

Updated Dec. 25, 2025 6:43 p.m. ET

Data Skrive

In a matchup featuring two teams coming off wins, the Los Angeles Chargers (11-4) will play the Houston Texans (10-5). The Chargers have taken four in a row, the Texans seven in a row. Los Angeles is a slim favorite (-2.5). The total for this one is set at 39.5 points.

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Chargers vs. Texans Odds & Betting Lines

Chargers vs Texans Betting Information updated as of December 24, 2025, 11:33 a.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Chargers	-2.5	-108	-123	39.5	-108	-112

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Chargers vs. Texans Prediction & Pick

Pick ATS: Texans (+2.5)
Pick OU: Over (39.5)
Prediction: Texans 24 - Chargers 18

How to Watch Los Angeles vs. Houston

Game date: Saturday, December 27, 2025
Time: 4:30 p.m. ET
Venue: SoFi Stadium
Location: Inglewood, California
TV: NFL Network
Live Boxscore: FOX Sports

Chargers vs. Texans Recent Matchups

In their past four head-to-head bouts, Houston has won against Los Angeles three times.
In their last four head-to-head matchups, Houston has scored 124 points versus Los Angeles, while surrendering only 95 points.

Los Angeles Betting Info

Los Angeles has played 15 games, posting nine wins against the spread.
The Chargers are 5-6 ATS this season when playing as at least 2.5-point favorites.
Los Angeles has combined with its opponent to eclipse the over/under in 40% of its contests this year (six times over 15 games with a set point total).
The Chargers have a 7-4 record in games they played as moneyline favorite (winning 63.6% of those games).
Looking at this game's moneyline, the Chargers' implied win probability is 55.6%.

Chargers Stats

Stat	Average (Total)	Rank
Pass yards	220.2 (3,303)	13
Rush yards	125.3 (1,880)	6
Points scored	23.3 (349)	16
Pass yards against	179.3 (2,690)	6
Rush yards against	103.8 (1,557)	10
Points allowed	20.1 (301)	8

Los Angeles' Key Players

Offense

Justin Herbert has thrown for 3,491 yards (eighth in the NFL), 25 touchdowns (fifth in the NFL) and 12 interceptions this year. He is averaging 232.7 yards per game and 7.3 per attempt, while completing 66.5% of his passes.
He has tacked on 461 rushing yards (30.7 per game) and two touchdowns on the ground.
Ladd McConkey has 65 catches for 758 yards and six TDs. Through 15 games, he is averaging 4.3 catches and 50.5 yards per game.
In the passing attack, Quentin Johnston, has totaled 637 receiving yards and eight touchdowns (eighth in the NFL) after grabbing 46 balls on 77 targets. Per game, he's averaging 53.1 yards and 3.8 receptions in 12 games.
In the ground game, Kimani Vidal averages 4.2 yards per attempt (28th in the NFL) and 52.6 yards per game for 631 total rushing yards. He has recorded three rushing touchdowns this season.
Vidal has been targeted 21 times and turned those targets into 15 catches, 138 yards and one TD.

Defense

On the defensive side, Tuli Tuipulotu has 43 tackles, 20.0 TFL, and 13 sacks in 2025.
Daiyan Henley has intercepted two pases and added 90 tackles, 5.0 TFL, 3.5 sacks, and five passes defended.
Derwin James has totaled two interceptions and also has 86 tackles, 6.0 TFL, two sacks, and six passes defended.
So far this season, Odafe Oweh has 33 tackles, 9.0 TFL, and seven sacks.

Houston Betting Info

Houston is 8-7-0 against the spread this season.
So far this year, the Texans have been installed as underdogs by a 2.5-point margin or more five times and are 3-2 ATS in those matchups.
Games involving Houston have hit the over on five occasions this season.
The Texans have won four of the seven games they've played as underdogs this season.
The moneyline for this contest implies a 48.8% chance of a victory for the Texans.

Texans Stats

Stat	Average (Total)	Rank
Pass yards	217.2 (3,258)	16
Rush yards	106.7 (1,600)	23
Points scored	23.1 (346)	19
Pass yards against	176.1 (2,641)	4
Rush yards against	96.2 (1,443)	4
Points allowed	16.6 (249)	1

Houston's Key Players

Offense

C.J. Stroud has thrown for 2,628 yards this year, with 16 touchdowns and six interceptions. He is completing 65.3% of his attempts while averaging 219.0 yards per game and 7.1 per attempt.
He's added 204 yards on the ground (third on the Texans), while scoring zero rushing touchdowns. He's averaging 17.0 yards per game and 4.9 per attempt.
Nico Collins has 68 catches for 1,060 yards (eighth in the NFL) and six receiving touchdowns. He has been targeted 116 times and averages 4.9 receptions per game through 14 games played.
Woody Marks is averaging 41.7 rushing yards per game this season (584 total yards), while scoring two rushing touchdowns.
In addition to his ground game, Marks has grabbed 21 passes (on 31 targets) for 204 yards (seventh on the Texans), with three receiving touchdowns. He averages 14.6 yards per game.
Dalton Schultz has been targeted 98 times, resulting in 75 catches for 685 yards .

Defense

Will Anderson Jr. has 45 tackles, 17.0 TFL, 11.5 sacks, and three passes defended in 2025.
Danielle Hunter has 13.0 sacks in addition to his 13.0 TFL and 48 tackles over 14 games. He's third in the NFL in sacks.
Kamari Lassiter has 7.0 TFL, 85 tackles, and four interceptions in the 2025 campaign.
Azeez Al-Shaair has put up 1.0 TFL, 96 tackles, and one interception through 14 games.