2025-26 San Francisco 49ers Odds: Odds to win Super Bowl, NFL Playoffs, Division

Updated Jan. 10, 2026 12:31 a.m. ET

Data Skrive

The San Francisco 49ers have +3000 odds to win the Super Bowl, 12th-ranked in the NFL as of Jan. 10.

In their last outing, the 49ers lost 13-3 to the Seattle Seahawks. Brock Purdy had 127 yards on 19-of-27 passing (70.4%), with no touchdowns and one interception. He also carried the ball two times for 21 yards. Christian McCaffrey took eight carries for 23 yards (2.9 yards per carry), while adding six receptions for 34 yards in the passing game. Jauan Jennings recorded four receptions for 35 yards (averaging 8.8 per catch).

49ers Postseason Odds

Odds to win the Super Bowl: +3000 (Bet $100 to win $3,000)

Learn more about the San Francisco 49ers on Fox Sports.

49ers Super Bowl Odds Insights

While our computer ranking places the 49ers fifth-best in the league in terms of winning the Super Bowl, the team's Super Bowl odds rank comes in significantly worse, ranking them 12th-best.
After having +1900 odds to win the Super Bowl before the season, the 49ers' current odds have worsened to +3000 (seventh-smallest change in the league).
Based on their current odds (+3000), the 49ers have a 3.2% chance of winning the Super Bowl.

49ers Betting Insights

The 49ers have put together an 11-6-0 ATS record this year.
San Francisco games have hit the over 10 out of 17 times this season.
The 49ers have compiled an 11-1 record in games they were listed as the moneyline favorite (winning 91.7% of those games).
This season, San Francisco has been the underdog five times and won one of those games.

49ers Top Players

Purdy has put up 2,167 passing yards (240.8 YPG) with a 69.4% completion percentage (197-for-284) while firing 20 touchdowns and 10 interceptions. He also has 147 rushing yards via 33 attempts and three rushing touchdowns.
McCaffrey has taken 311 carries for a team-high 1,202 rushing yards (70.7 yards per game) and 10 touchdowns. He's also caught 102 passes for 924 yards with seven touchdowns through the air.
McCaffrey's game status for Sunday's Wild Card matchup against the Eagles is unknown.
Brian Robinson Jr. has 400 rushing yards on 92 attempts, and two touchdowns.
Jennings has been targeted 90 times and tacked on 643 yards (on 55 catches) plus nine touchdowns.
George Kittle has totaled 628 yards on 57 receptions with seven touchdowns, averaging 57.1 yards per game.
Kittle's game status for Sunday's Wild Card matchup against the Eagles is unknown.
Clelin Ferrell has 4.0 sacks to lead the team, and has also racked up 4.0 TFL and 25 tackles.
This season Dee Winters has collected 101 tackles, 8.0 TFL, and one interception, leading his team in tackles.
Winters is considered questionable for the upcoming matchup against the Eagles on Sunday.
This season Ji'Ayir Brown leads the team with two interceptions and has added 63 tackles, 2.0 TFL, and six passes defended.
Brown's game status for Sunday's Wild Card matchup against the Eagles is unknown.

49ers 2025-26 Schedule

Opponent	Week	Date	Opponent Power Ranking	Favorite	Total
@ Seahawks	1	Sept. 7	1st	49ers (-1.5)	43.5
@ Saints	2	Sept. 14	23rd	49ers (-3)	40.5
Cardinals	3	Sept. 21	28th	49ers (-1.5)	44.5
Jaguars	4	Sept. 28	3rd	49ers (-3.5)	45.5
@ Rams	5	Oct. 2	2nd	Rams (-8.5)	43.5
@ Buccaneers	6	Oct. 12	18th	Buccaneers (-3.5)	46.5
Falcons	7	Oct. 19	19th	49ers (-1.5)	46.5
@ Texans	8	Oct. 26	4th	Texans (-2.5)	42.5
@ Giants	9	Nov. 2	22nd	49ers (-2.5)	47.5
Rams	10	Nov. 9	2nd	Rams (-5.5)	49.5
@ Cardinals	11	Nov. 16	28th	49ers (-3.5)	48.5
Panthers	12	Nov. 24	20th	49ers (-7.5)	49.5
@ Browns	13	Nov. 30	29th	49ers (-5.5)	35.5
Titans	15	Dec. 14	30th	49ers (-12.5)	44.5
@ Colts	16	Dec. 22	10th	49ers (-4.5)	46.5
Bears	17	Dec. 28	12th	49ers (-3.5)	51.5
Seahawks	18	Jan. 3	1st	Seahawks (-2.5)	48.5
@ Eagles	WC	Jan. 11	9th	Eagles (-5.5)	44.5