Reds vs. Diamondbacks Prediction, Odds, Picks - August 23

Jalen Beeks gets the nod on the mound for the Arizona Diamondbacks against the Cincinnati Reds and Miguel Andujar on Saturday at 8:10 p.m. ET. The favored Reds have -120 moneyline odds against the underdog Diamondbacks, who are listed at +100. Cincinnati is the run-line favorite (-1.5). The contest's total is set at 9 runs.

Take a look at everything you need to know from a betting perspective on the Reds-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. Diamondbacks Highlights | MLB on FOX

Check out the best moments between the Cleveland Guardians and the Arizona Diamondbacks.

Reds vs. Diamondbacks Game Information & Odds

• When: Saturday, August 23, 2025 at 8:10 p.m. ET
• Where: Chase Field in Phoenix, Arizona
• How to watch on TV: ARID and FDSOH

Reds vs. Diamondbacks Prediction

• Score Prediction: Diamondbacks 5, Reds 4
• Total Prediction: Over 9 runs
• Win Probabilities: Reds 52%, Diamondbacks 48%

Reds vs. Diamondbacks Betting Insights

• This season, the Reds have won 30 out of the 56 games, or 53.6%, in which they've been favored.
• Cincinnati has entered 44 games this season favored by -120 or more and is 24-20 in those contests.
• The sportsbooks' moneyline implies a 54.5% chance of a victory for the Reds.
• The Diamondbacks have come away with 22 wins in the 49 contests they have been listed as the underdogs in this season.
• This year, Arizona has won 21 of 43 games when listed as at least +100 or worse on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Diamondbacks have a 50% chance of pulling out a win.

Reds Recent Betting Performance

• The Reds were the moneyline favorite for four of their last 10 games, and went 3-1 in those matchups.
• In their last 10 outings, the Reds and their opponents combined to hit the over on the run total four times (all 10 games had set totals).
• The Reds have a 7-3-0 record against the spread over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz has gone yard 19 times in the 2025 campaign while knocking in 77 runs, both totals that lead the Reds.
• De La Cruz is 56th in homers and 21st in RBI among all batters in MLB.
• TJ Friedl has 18 doubles, two triples, 10 home runs and 60 walks while hitting .266.
• Friedl is 164th in home runs and 178th in RBI on the year.
• Friedl carries a four-game streak with at least one hit into this matchup. During his last five outings he is hitting .190 with two walks and an RBI.
• Spencer Steer is hitting .235 with 17 doubles, two triples, 15 home runs and 38 walks.
• Andujar is batting .315 with 15 doubles, a triple, nine home runs and 15 walks.
• Andujar has recorded at least one hit in three straight games. In his last five games he is batting .389 with three doubles and two RBIs.

Reds Team Props

Diamondbacks Recent Betting Performance

• The Diamondbacks have been underdogs twice in the last 10 games and won both contests.
• In their last 10 games with a total, the Diamondbacks and their opponents are 4-6-0 when it comes to hitting the over.
• The Diamondbacks have a record of 5-5-0 ATS over their last 10 games.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Geraldo Perdomo has driven in the most runs for the Diamondbacks with 81 runs batted in.
• Perdomo's home run total places him 122nd in MLB, and he ranks 17th in RBI.
• Corbin Carroll has put his power on display as he leads his team with 27 home runs.
• Among all MLB hitters, Carroll is 14th in home runs and 52nd in RBI.
• Ketel Marte leads the Diamondbacks with a team-best batting average of .292.
• Lourdes Gurriel Jr. is hitting .249 with 23 doubles, two triples, 17 home runs and 29 walks.

Diamondbacks Team Props

Guardians vs. Diamondbacks Highlights | MLB on FOX

Check out the best moments between the Cleveland Guardians and the Arizona Diamondbacks.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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