Red Sox vs. Diamondbacks Prediction, Odds, Picks - September 6

Jarren Duran and Geraldo Perdomo will be among the stars on display when the Boston Red Sox face the Arizona Diamondbacks on Saturday at 8:10 p.m. ET, at Chase Field. The Red Sox have been listed as -114 moneyline favorites in this matchup with the Diamondbacks (-105). Boston is favored on the run line (-1.5 with +142 odds). A 9-run total has been set in this matchup.

Here is everything you need from a betting perspective on the Red Sox-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Diamondbacks Game Information & Odds

• When: Saturday, September 6, 2025 at 8:10 p.m. ET
• Where: Chase Field in Phoenix, Arizona
• How to watch on TV: ARID and NESN

Red Sox vs. Diamondbacks Prediction

• Score Prediction: Diamondbacks 6, Red Sox 5
• Total Prediction: Over 9 runs
• Win Probabilities: Red Sox 50%, Diamondbacks 50%

Red Sox vs. Diamondbacks Betting Insights

• This season, the Red Sox have been favored 88 times and won 52, or 59.1%, of those games.
• This season Boston has won 50 of its 85 games, or 58.8%, when favored by at least -114 on the moneyline.
• The Red Sox have a 53.3% chance to win this game based on the implied probability of the moneyline.
• The Diamondbacks have been underdogs in 58 games this season and have come away with the win 28 times (48.3%) in those contests.
• This season, Arizona has come away with a win 27 times in 55 chances when named as an underdog of at least -105 or longer on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Diamondbacks have a 51.2% chance of pulling out a win.

Red Sox Recent Betting Performance

• The Red Sox went 6-4 over the 10 games they were moneyline favorites in their last 10 matchups.
• Over their last 10 matchups, the Red Sox and their opponents combined to hit the over on the total four times (all 10 games had set totals).
• The Red Sox's ATS record is 4-6-0 over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Duran is outstanding at both finding his way aboard and doing damage when he's at the plate. Duran leads the Red Sox this season with a .336 OBP, .446 slugging percentage, and 140 base hits.
• In all of MLB, Duran is 133rd in homers and 37th in RBI.
• Trevor Story has hit 23 home runs with 88 runs batted in while hitting .259. Those stats are all team-highs.
• Story ranks 43rd in homers in baseball, and 17th in RBI.
• Ceddanne Rafaela has 29 doubles, three triples, 16 home runs and 22 walks while batting .246.
• Alex Bregman has 26 doubles, 16 home runs and 39 walks while hitting .284.

Red Sox Team Props

Diamondbacks Recent Betting Performance

• The Diamondbacks have played as underdogs in seven of their past 10 games and won five of those contests.
• In their last 10 games with a total, the Diamondbacks and their opponents have combined to hit the over four times.
• The Diamondbacks have nine wins against the spread in their last 10 chances.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Perdomo has sent home a team-high 90 runs batted in.
• Perdomo's home run total puts him 94th in MLB, and he ranks 15th in RBI.
• Corbin Carroll has shown his power as he leads his team with 30 home runs.
• Carroll ranks 12th overall in homers and 45th in RBI this season.
• Ketel Marte paces the Diamondbacks with a team-high batting average of .288.
• Gabriel Moreno is hitting .274 with 10 doubles, a triple, seven home runs and 17 walks.

Diamondbacks Team Props

Diamondback vs. Brewers Highlights | MLB on FOX

Check out the best moments between the Arizona Diamondbacks and the Milwaukee Brewers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Arizona Diamondbacks

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