Pirates vs. White Sox Prediction, Odds, Picks - July 18

Nick Gonzales and the Pittsburgh Pirates play Lenyn Sosa and the Chicago White Sox on Friday at 6:40 p.m. ET, in the first of a three-game series at PNC Park. The favored Pirates have -162 moneyline odds to win against the underdog White Sox, who are listed at +136. Pittsburgh is favored on the run line (-1.5 with +134 odds). The game's total has been set at 8.5 runs.

Here's everything you need to know from a betting perspective on the Pirates-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Pirates vs. White Sox Game Information & Odds

• When: Friday, July 18, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and CHSN

Pirates vs. White Sox Prediction

• Score Prediction: Pirates 4, White Sox 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Pirates 56%, White Sox 44%

Pirates vs. White Sox Betting Insights

• This season, the Pirates have been favored 25 times and won 12, or 48%, of those games.
• Pittsburgh has a record of 1-2 in games when sportsbooks favor them by at least -162 on the moneyline.
• The Pirates have a 61.8% chance to win this game based on the implied probability of the moneyline.
• The White Sox have won in 31, or 32.6%, of the 95 contests they have been named as odds-on underdogs this year.
• Chicago has a win-loss record of 20-45 when favored by +136 or worse by bookmakers this year.
• Oddsmakers have implied with the moneyline set for this matchup that the White Sox have a 42.4% chance of pulling out a win.

Pirates Recent Betting Performance

• The Pirates have not been favored on the moneyline over the last 10 games.
• In their last 10 matchups (all had set totals), the Pirates combined with their opponents to hit the over on the total two times.
• The Pirates' ATS record is 6-4-0 over their past 10 games.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz has gone yard 16 times this season, the highest mark on the Pirates, while hitting .212 with 37 RBI.
• Among all hitters in baseball, Cruz's home run total places him 43rd, and his RBI tally ranks him 117th.
• Cruz has collected a hit in five straight games. In his last five games he is hitting .375 with a double, a home run, a walk and two RBIs.
• Andrew McCutchen is hitting .255 to lead his team.
• McCutchen ranks 152nd in home runs in MLB, and 162nd in RBI.
• Bryan Reynolds has accumulated a team-high 46 runs batted in.
• Reynolds will look to build on his two-game hitting in this game. During his last five outings he is hitting .158 with a double and an RBI.
• Isiah Kiner-Falefa is hitting .274 with 11 doubles, two triples, a home run and 14 walks.

Pirates Team Props

White Sox Recent Betting Performance

• In eight games over the last 10 matchups when set as underdogs by oddsmakers, the White Sox had a record of 3-5.
• In their last 10 games with a total, the White Sox and their opponents have combined to hit the over four times.
• The White Sox have a record of 4-6-0 ATS over their last 10 games.

White Sox Recent Stats

White Sox Player Insights

• Miguel Vargas leads the White Sox with 35 runs batted in while putting up a team-high batting average of .218.
• Among all hitters in the majors, Vargas' home run total is 121st and his RBI tally is 131st.
• Andrew Benintendi has been a reliable source of runs this year, leading the lineup with 11 home runs and 35 runs batted in.
• Benintendi ranks 101st overall in home runs and 131st in RBI this season.
• Chase Meidroth is hitting .243 with seven doubles, two home runs and 32 walks.
• Sosa is batting .267 with 14 doubles, a triple, nine home runs and eight walks.

White Sox Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Pittsburgh Pirates

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