Pirates vs. Reds Prediction, Odds, Picks - August 10

Liover Peguero and the Pittsburgh Pirates take the field on Sunday at PNC Park against Zack Littell, who is starting for the Cincinnati Reds. First pitch is set for 1:35 p.m. ET for the final game of a four-game series. The Pirates have been listed as -112 moneyline favorites for this matchup with the Reds (-108). Cincinnati is a 1.5-run favorite (at +155 odds). An 8-run over/under has been set for the matchup.

Here is everything you need to know from a betting perspective on the Pirates-Reds game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

AJ Pierzynski reacts to MLB All-Star Game Hits & Misses - Swing-Off | FULL INTERVIEW | The Herd

A.J. Pierzynski joins Colin Cowherd for an All-Star Game debrief. He dives into the robot umpire system's impact on catcher framing and his take on its future. Pierzynski also unpacks the pitch clock's surprising success, defends Ben Mezley's controversial All-Star nod, and weighs in on Cal Raleigh's historic homer chase. Plus, hear his candid thoughts on the Yankees' trade deadline needs and the Dodgers' recent struggles.

Pirates vs. Reds Game Information & Odds

• When: Sunday, August 10, 2025 at 1:35 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: MLB Network, SportsNet PT, and FDSOH

Pirates vs. Reds Prediction

• Score Prediction: Pirates 5, Reds 4
• Total Prediction: Over 8 runs
• Win Probabilities: Pirates 51%, Reds 49%

Pirates vs. Reds Betting Insights

• This season, the Pirates have won 16 out of the 34 games, or 47.1%, in which they've been favored.
• Pittsburgh is 16-17 this season when entering a game favored by -112 or more on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Pirates have a 52.8% chance to win.
• The Reds have been underdogs in 62 games this season and have come away with the win 32 times (51.6%) in those contests.
• This season, Cincinnati has come away with a win 31 times in 59 chances when named as an underdog of at least -108 or worse on the moneyline.
• The Reds have an implied victory probability of 51.9% according to the moneyline set for this matchup.

Pirates Recent Betting Performance

• The Pirates were favored on the moneyline in four of their last 10 games, and they finished 2-2 in those matchups.
• In their last 10 matchups, the Pirates and their opponents combined to hit the over six times (all 10 of the games had set totals).
• The Pirates' ATS record is 6-4-0 over their past 10 games.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz has a team-best 18 home runs.
• In all of the majors, Cruz ranks 48th in homers and 92nd in RBI.
• Bryan Reynolds has capitalized on opportunities as he paces his team with 56 RBI.
• Reynolds is 133rd in home runs in baseball, and 65th in RBI.
• Andrew McCutchen leads the Pirates with a team-best batting average of .247.
• Isiah Kiner-Falefa is batting .268 with 14 doubles, two triples, a home run and 16 walks.

Pirates Team Props

Reds Recent Betting Performance

• In six games as underdogs over the last 10 matchups, the Reds have a record of 3-3.
• In their last 10 games with a total, the Reds and their opponents are 2-7-1 when it comes to hitting the over.
• The Reds have a record of 4-6-0 ATS over their last 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz leads the Reds with 19 home runs and 73 runs batted in, while recording a team-high batting average of .276.
• De La Cruz's home run total places him 42nd in MLB, and he is 16th in RBI.
• TJ Friedl has 17 doubles, two triples, 10 home runs and 55 walks while batting .274.
• Friedl is currently 150th in home runs and 168th in RBI in the big leagues.
• Spencer Steer is batting .237 with 15 doubles, two triples, 13 home runs and 32 walks.
• Matt McLain has 12 doubles, 11 home runs and 42 walks while batting .227.

Reds Team Props

AJ Pierzynski reacts to MLB All-Star Game Hits & Misses - Swing-Off | FULL INTERVIEW | The Herd

A.J. Pierzynski joins Colin Cowherd for an All-Star Game debrief. He dives into the robot umpire system's impact on catcher framing and his take on its future. Pierzynski also unpacks the pitch clock's surprising success, defends Ben Mezley's controversial All-Star nod, and weighs in on Cal Raleigh's historic homer chase. Plus, hear his candid thoughts on the Yankees' trade deadline needs and the Dodgers' recent struggles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Pittsburgh Pirates

Cincinnati Reds