Orioles vs. Pirates Prediction, Odds, Picks - April 5

Gunnar Henderson and Ke'Bryan Hayes will be among the star attractions when the Baltimore Orioles play the Pittsburgh Pirates on Friday at 4:12 PM ET, at PNC Park. Oddsmakers list the Orioles as -121 moneyline favorites, while giving the underdog Pirates +102 moneyline odds to win. Baltimore (-1.5) is favored on the run line. The total is 7.5 runs for the contest.

Here's everything you need from a betting perspective on the Orioles-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Pirates Game Information & Odds

• When: Friday, April 5, 2024 at 4:12 PM ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to Watch on TV: MASN2

Orioles vs. Pirates Prediction

• Score Prediction: Orioles 5, Pirates 3
• Total Prediction: Over 7.5 runs
• Win Probabilities: Orioles 64%, Pirates 36%

Orioles vs. Pirates Betting Insights

• This season, the Orioles have been favored six times and won four of those games.
• Baltimore has a record of 4-2 in games when bookmakers favor them by at least -121 on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Orioles have a 54.8% chance to win.
• The Pirates have been listed as the underdog four times this season and have come away with a win in all of those games.
• Pittsburgh has yet to lose in three games when named as moneyline underdog of +102 or worse.
• The moneyline set for this matchup implies the Pirates have a 49.5% chance of coming away with a victory in the contest.

Orioles Player Insights

• The Orioles best hitter so far this season is Adley Rutschman, who's hitting at a team-leading .333 rate along with zero homers and three RBI.
• Rutschman ranks 150th in homers and 94th in RBI among all batters in baseball.
• Ryan Mountcastle has two doubles, a home run and four walks while hitting .300.
• Mountcastle is 49th in homers and 15th in RBI on the year.
• Henderson has a triple, a home run and three walks while batting .238.
• Anthony Santander has hit two home runs with eight runs batted in. Both lead his team.

Orioles Team Props

Learn more about this Orioles vs. Pirates matchup on Fox Sports.

Pirates Player Insights

• Connor Joe has swatted a team-high one long balls.
• Among all hitters in MLB, Joe's home run total ranks 49th and his RBI tally is 15th.
• Joe has collected a hit in five games in a row. In his last five games he is hitting .409 with four doubles, a home run, three walks and seven RBI.
• Bryan Reynolds has been a reliable source of runs this year, leading the lineup with one home runs and nine RBI.
• Reynolds is 49th among all hitters in MLB in home runs, and fifth in RBI.
• Hayes is hitting .290 with three doubles and six walks.
• Michael A. Taylor paces the Pirates with a .480 batting average.

Pirates Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.