Guardians vs. Brewers Prediction, Odds, Picks - May 13

The Milwaukee Brewers and Jackson Chourio square off against Jose Ramirez and the Cleveland Guardians on Tuesday, in the second game of a three-game series at Progressive Field. The Guardians are the favorite in this one, at -135, while the underdog Brewers have +114 odds to upset. Cleveland is the favorite on the run line (-1.5 with +146 odds). The game's total is set at 9 runs.

Here's everything you need from a betting perspective on the Guardians-Brewers game, regarding the run line, moneyline and total, plus expert picks.

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Brewers vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Milwaukee Brewers and the Cleveland Guardians!

Guardians vs. Brewers Game Information & Odds

• When: Tuesday, May 13, 2025 at 6:10 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and FDSWI

Guardians vs. Brewers Prediction

• Score Prediction: Guardians 6, Brewers 5
• Total Prediction: Over 9 runs
• Win Probabilities: Guardians 52%, Brewers 48%

Guardians vs. Brewers Betting Insights

• This season, the Guardians have been favored 15 times and won 11, or 73.3%, of those games.
• Cleveland has a record of 3-1 in games when bookmakers favor them by at least -135 on the moneyline.
• The sportsbooks' moneyline implies a 57.4% chance of a victory for the Guardians.
• The Brewers have been victorious in six, or 28.6%, of the 21 contests they have been chosen as underdogs in this season.
• This season, Milwaukee has come away with a win three times in 13 chances when named as an underdog of at least +114 or longer on the moneyline.
• The Brewers have an implied victory probability of 46.7% according to the moneyline set for this matchup.

Guardians Recent Betting Performance

• The Guardians have a 2-1 record from the three games they were moneyline favorites over their last 10 matchups.
• Over their last 10 outings, the Guardians and their opponents combined to go over the run total four times (all 10 of the games had set totals).
• The Guardians are 5-5-0 against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Steven Kwan leads the Guardians with a .329 batting average.
• In all of Major League Baseball, Kwan is 119th in home runs and 109th in RBI.
• Kwan carries a two-game hitting streak into this matchup. In his last five games he is hitting .294 with a double and four walks.
• Ramirez is hitting .289 with eight doubles, six home runs and 15 walks.
• Ramirez ranks 61st in home runs and 93rd in RBI among all MLB hitters this season.
• Ramirez enters this matchup looking for his eighth game in a row with a hit. In his last 10 games he is hitting .361 with three doubles, a home run, six walks and four RBIs.
• Kyle Manzardo paces the Guardians in home runs (nine) and runs batted in (23).
• Carlos Santana has three doubles, four home runs and 19 walks while hitting .223.

Guardians Team Props

Brewers Recent Betting Performance

• In six games as underdogs over the last 10 matchups, the Brewers have a record of 2-4.
• In their last 10 games with a total, the Brewers and their opponents have failed to hit the over eight times.
• The Brewers have won four of their last 10 games against the spread.

Brewers Recent Stats

Brewers Player Insights

• Chourio has put up a team-best seven home runs.
• Chourio's home run total places him 41st in the majors, and he ranks 27th in RBI.
• Brice Turang's .295 batting average paces his team.
• Turang ranks 154th in home runs and 127th in RBI among all major league hitters this year.
• William Contreras is hitting .230 with two doubles, four home runs and 24 walks.
• Christian Yelich has posted a team-high seven home runs and has driven in 26 runs.

Brewers Team Props

Brewers vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Milwaukee Brewers and the Cleveland Guardians!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cleveland Guardians

Milwaukee Brewers