Cubs vs. Pirates Prediction, Odds, Picks - August 15

Seiya Suzuki and the Chicago Cubs will square off against Bryan Reynolds and the Pittsburgh Pirates at Wrigley Field on Friday at 2:20 p.m. ET, in the first game of a three-game series. The Cubs are favored in this one, at -193, while the underdog Pirates have +160 odds to play spoiler. Chicago is favored on the run line (-1.5 with +102 odds). The over/under is 8.5 runs for this contest.

Take a look at everything you need to know from a betting perspective on the Cubs-Pirates game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Cubs vs. Blue Jays Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and Toronto Blue Jays.

Cubs vs. Pirates Game Information & Odds

• When: Friday, August 15, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MLB Network, MARQ, and SportsNet PT

Cubs vs. Pirates Prediction

• Score Prediction: Cubs 5, Pirates 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Cubs 58%, Pirates 42%

Cubs vs. Pirates Betting Insights

• This season, the Cubs have won 54 out of the 84 games, or 64.3%, in which they've been favored.
• Chicago has entered 15 games this season favored by -193 or more and is 13-2 in those contests.
• The moneyline for this contest implies a 65.9% chance of a victory for the Cubs.
• The Pirates have been underdogs in 84 games this season and have come away with the win 34 times (40.5%) in those contests.
• Pittsburgh has a mark of 6-13 in contests where sportsbooks favor it by +160 or worse on the moneyline.
• The Pirates have an implied victory probability of 38.5% according to the moneyline set by oddsmakers for this matchup.

Cubs Recent Betting Performance

• The Cubs were the moneyline favorite for eight of their last 10 games, and went 3-5 in those matchups.
• In their last 10 outings, the Cubs and their opponents combined to hit the over on the total one time (all 10 games had set totals).
• The Cubs' record against the spread is 4-6-0 over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is hitting .265 with 21 doubles, four triples, 18 home runs and 77 walks.
• Tucker's home runs rank him 53rd in the majors, and he ranks 54th in RBI.
• Pete Crow-Armstrong has shown off his power as he leads his team with 27 home runs.
• Crow-Armstrong ranks 11th in homers and 15th in RBI among all hitters in MLB.
• Suzuki has a team-high 27 home runs and 85 runs batted in.
• Nico Hoerner's .293 batting average leads his team.
• Hoerner is riding a two-game hitting streak into this one. In his last five games he is hitting .300 with .

Cubs Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs in eight of their past 10 games and won two of those contests.
• The Pirates and their opponents have combined to hit the over six times in their last 10 games with a total.
• The Pirates have a record of 4-6-0 ATS over their last 10 games.

Pirates Recent Stats

Pirates Player Insights

• Reynolds has put up a team-high 61 runs batted in.
• Reynolds is 112th in homers and 57th in RBI among all batters in the big leagues.
• Reynolds has collected a hit in four games in a row. During his last five outings he is hitting .368 with a double, two home runs, two walks and five RBIs.
• Andrew McCutchen is hitting .243 with 16 doubles, 11 home runs and 48 walks.
• Among all major league hitters, McCutchen ranks 142nd in homers and 164th in RBI.
• Isiah Kiner-Falefa has put up a team-high batting average of .268.
• Tommy Pham is hitting .263 with 12 doubles, a triple, five home runs and 32 walks.

Pirates Team Props

Cubs vs. Blue Jays Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and Toronto Blue Jays.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Chicago Cubs

Pittsburgh Pirates