Brewers vs. Angels Prediction, Odds, Picks - September 16

Caleb Durbin and the Milwaukee Brewers square off against Jo Adell and the Los Angeles Angels on Tuesday at 7:40 p.m. ET, in the first of a three-game series at American Family Field. The Brewers are listed as -275 moneyline favorites for this matchup with the Angels (+222). Milwaukee is favored on the run line (-1.5 with -129 odds). The game's over/under has been listed at 8.5 runs.

Check out everything you need from a betting perspective on the Brewers-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Brewers vs. Angels Game Information & Odds

• When: Tuesday, September 16, 2025 at 7:40 p.m. ET
• Where: American Family Field in Milwaukee, Wisconsin
• How to watch on TV: FDSWI

Brewers vs. Angels Prediction

• Score Prediction: Brewers 5, Angels 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Brewers 61%, Angels 39%

Brewers vs. Angels Betting Insights

• This season, the Brewers have won 55 out of the 86 games, or 64%, in which they've been favored.
• Milwaukee is undefeated in three games this season when favored by -275 or more on the moneyline.
• The bookmakers' moneyline implies a 73.3% chance of a victory for the Brewers.
• The Angels have been victorious in 51, or 45.1%, of the 113 contests they have been chosen as underdogs in this season.
• Los Angeles has a mark of 1-2 in contests where oddsmakers favor it by +222 or worse on the moneyline.
• The moneyline set for this matchup implies the Angels have a 31.1% chance of walking away with the win.

Brewers Recent Betting Performance

• The Brewers have a 5-4 record across the nine games they were a moneyline favorite in their last 10 matchups.
• In their last 10 matchups -- all had a set run total -- the Brewers and their opponents combined to go over the total five times.
• The Brewers have gone 4-6-0 against the spread over their past 10 games.

Brewers Recent Stats

Brewers Player Insights

• Brice Turang is batting .286 with 25 doubles, two triples, 18 home runs and 57 walks.
• In all of Major League Baseball, Turang is 94th in home runs and 53rd in RBI.
• William Contreras is batting .263 with 26 doubles, 17 home runs and 79 walks.
• Of all major league hitters, Contreras is 101st in home runs and 59th in RBI.
• Christian Yelich has put up a team-best 28 home runs and 96 runs batted in.
• Jackson Chourio is batting .280 with 33 doubles, four triples, 20 home runs and 27 walks.

Brewers Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in six of their past 10 games and have gone 2-4 in those contests.
• In their last 10 games with a total, the Angels and their opponents are 7-3-0 when it comes to hitting the over.
• The Angels have a record of 4-6-0 ATS over their last 10 games.

Angels Recent Stats

Angels Player Insights

• Taylor Ward has racked up a team-leading 98 runs batted in.
• Among all hitters in MLB, Ward's home run total is 12th and his RBI tally is 10th.
• Adell has racked up a team-best 36 home runs.
• Adell is currently eighth in home runs and 14th in RBI in the big leagues.
• Zach Neto has 29 doubles, a triple, 26 home runs and 33 walks while batting .257.
• Mike Trout has 13 doubles, a triple, 21 home runs and 83 walks while hitting .231.

Angels Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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