Astros vs. Rangers Prediction, Odds, Picks - September 15

Jason Alexander and the Houston Astros will take the field against the Texas Rangers and projected starter Jack Leiter on Monday at Daikin Park. The Rangers are +111 moneyline underdogs in this matchup with the favored Astros (-131). Houston is the favorite on the run line (-1.5 with +157 odds). The over/under for the game is listed at 8.5 runs.

Check out everything you need to know from a betting perspective on the Astros-Rangers game, regarding the run line, moneyline and total, plus expert picks.

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Astros vs. Rangers Game Information & Odds

• When: Monday, September 15, 2025 at 8:10 p.m. ET
• Where: Daikin Park in Houston, Texas
• How to watch on TV: SCHN and RSN

Astros vs. Rangers Prediction

• Score Prediction: Astros 5, Rangers 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Astros 51%, Rangers 49%

Astros vs. Rangers Betting Insights

• The Astros have won 51, or 52.6%, of the 97 games they've played as favorites this season.
• This season Houston has won 33 of its 60 games, or 55%, when favored by at least -131 on the moneyline.
• The implied probability of a win from the Astros, based on the moneyline, is 56.7%.
• The Rangers have been underdogs in 75 games this season and have come away with the win 30 times (40%) in those contests.
• Texas has a mark of 11-23 in contests where sportsbooks favor it by +111 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Rangers have a 47.4% chance of pulling out a win.

Astros Recent Betting Performance

• The Astros have a 1-2 record from the three games they were moneyline favorites over their last 10 matchups.
• In their last 10 outings (all had set totals), the Astros combined with their opponents to hit the over on the run total four times.
• The Astros are 5-5-0 against the spread over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Jose Altuve paces the Astros with 25 home runs.
• Among all hitters in baseball, Altuve is 40th in homers and 71st in RBI.
• Altuve carries a two-game hitting streak into this matchup. In his last five games he is hitting .267 with a home run and an RBI.
• Jeremy Pena's .297 batting average paces his team.
• Among all major league hitters, Pena ranks 128th in homers and 125th in RBI.
• Pena enters this matchup looking for his fourth game in a row with a hit. During his last five outings he is hitting .174 with two doubles, a walk and two RBIs.
• Yainer Diaz is batting .259 with 22 doubles, a triple, 19 home runs and 20 walks.
• Diaz is on a two-game hitting streak entering this contest. During his last five outings he is batting .474 with two doubles, a home run and five RBIs.
• Christian Walker's 81 runs batted in are a team-high mark.
• Walker has recorded at least one hit in three straight games. In his last five games he is batting .368 with a home run, a walk and five RBIs.

Astros Team Props

Rangers Recent Betting Performance

• In seven games over the last 10 matchups when set as underdogs by bookmakers, the Rangers had a record of 5-2.
• The Rangers and their opponents have combined to hit the over four times in their last 10 games with a total.
• The Rangers have a record of 7-3-0 ATS over their last 10 games.

Rangers Recent Stats

Rangers Player Insights

• Wyatt Langford has racked up a team-best 21 home runs.
• Among all hitters in MLB, Langford ranks 64th in homers and 103rd in RBI.
• Josh Smith is hitting .257 to lead the lineup.
• Smith ranks 213th in homers and 244th in RBI among all batters in MLB.
• Adolis Garcia leads the Rangers with 73 runs batted in.
• Josh Jung has 19 doubles, a triple, 13 home runs and 25 walks while batting .248.

Rangers Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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