Utah vs. Colorado Prediction, Odds, Picks - October 25, 2025

Updated Oct. 25, 2025 9:04 p.m. ET

Data Skrive

Big 12 opponents meet when the Utah Utes (5-2) host the Colorado Buffaloes (3-4) on Saturday, October 25, 2025 at Rice-Eccles Stadium. Utah is favored by two touchdowns. The over/under is set at 49.

In their most recent action, the Utes lost against the BYU Cougars, 24-21. The Buffaloes won versus the Iowa State Cyclones in their last game, 24-17.

Keep up with college football all season on FOX Sports.

Utah vs. Colorado Game Information & Odds

When: Saturday, October 25, 2025 at 10:15 p.m. ET
Location: Rice-Eccles Stadium in Salt Lake City, Utah
TV: ESPN
Live Box Score on FOX Sports

Utah vs Colorado Betting Information updated as of October 25, 2025, 1:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Utah	-14 (-111)	-613	+448	49	-110	-110

Utah vs. Colorado Prediction

Pick ATS: Utah (-14)
Pick OU: Under (49)
Prediction: Utah 33, Colorado 16

Predictions are made by the Data Skrive betting model.

Learn more about the Utah Utes vs. the Colorado Buffaloes game on FOX Sports!

Utah vs. Colorado Betting Insights

Per the spread and over/under, the implied score for the game is Utes 32, Buffaloes 18.
The Utes have an 86.0% chance to collect the win in this meeting per the moneyline's implied probability. The Buffaloes hold an 18.2% implied probability.
Utah has won five games against the spread this season, while failing to cover twice.
Colorado has covered four times in seven games with a spread this year.

Utah vs. Colorado: Head-to-Head

Utah holds a 3-1 record against Colorado in their last four matchups.
In those games against Utah, the Buffaloes have covered three times while going over the point total on two occasions.
Over their last four head-to-head matchups, Utah has scored 138 points, while Colorado has compiled 100.

Utah vs. Colorado: 2025 Stats Comparison

	Utah	Colorado
Off. Points per Game (Rank)	36.9 (28)	24.9 (99)
Def. Points per Game (Rank)	15.3 (11)	23.7 (51)
Turnovers Allowed (Rank)	8 (43)	8 (43)
Turnovers Forced (Rank)	7 (100)	6 (109)

Utah 2025 Key Players

Name	Position	Stats
Devon Dampier	QB	1,375 YDS (68.7%) / 13 TD / 4 INT 442 RUSH YDS / 5 RUSH TD / 63.1 RUSH YPG
Wayshawn Parker	RB	358 YDS / 3 TD / 51.1 YPG / 6 YPC 7 REC / 90 REC YDS / 2 REC TD / 15 REC YPG
NaQuari Rogers	RB	300 YDS / 6 TD / 42.9 YPG / 4.2 YPC 3 REC / 43 REC YDS / 0 REC TD / 14.3 REC YPG
Ryan Davis	WR	46 REC / 482 YDS / 3 TD / 68.9 YPG
John Henry Daley	DL	29 TKL / 8 TFL / 9 SACK
Jackson Bennee	DB	29 TKL / 1 TFL / 3 INT / 3 PD
Johnathan Hall	LB	33 TKL / 2 TFL / 1 INT / 1 PD
Logan Fano	DL	25 TKL / 4 TFL / 2 SACK

Colorado 2025 Key Players

Name	Position	Stats
Kaidon Salter	QB	1,156 YDS (65.5%) / 9 TD / 4 INT 271 RUSH YDS / 5 RUSH TD / 45.2 RUSH YPG
Omarion Miller	WR	20 REC / 371 YDS / 4 TD / 61.8 YPG
Joseph Williams	WR	24 REC / 370 YDS / 3 TD / 52.9 YPG
Micah Welch	RB	277 YDS / 2 TD / 39.6 YPG / 4.5 YPC
Keaten Wade	DL	23 TKL / 4 TFL / 2.5 SACK
Tawfiq Byard	DB	30 TKL / 1 TFL / 0.5 SACK / 1 INT
Jeremiah Brown	LB	30 TKL / 3 TFL
Reginald Hughes	LB	30 TKL / 0 TFL