Michigan State vs. UCLA Prediction, Odds, Picks - October 11, 2025

Updated Oct. 11, 2025 9:04 a.m. ET

Data Skrive

Big Ten rivals meet when the Michigan State Spartans (3-2) host the UCLA Bruins (1-4) on Saturday, October 11, 2025 at Spartan Stadium. Michigan State is favored by 7.5 points. The contest has a 52.5-point over/under.

In their last game, the Spartans lost versus the Nebraska Cornhuskers, 38-27. The Bruins won against the Penn State Nittany Lions in their most recent game, 42-37.

Keep up with college football all season on FOX Sports.

Michigan State vs. UCLA Game Information & Odds

When: Saturday, October 11, 2025 at 12 p.m. ET
Location: Spartan Stadium in East Lansing, Michigan
TV: BTN
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Michigan State vs UCLA Betting Information updated as of October 11, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Michigan State	-7.5 (-108)	-296	+238	52.5	-110	-110

Michigan State vs. UCLA Prediction

Pick ATS: Michigan State (-7.5)
Pick OU: Over (52.5)
Prediction: Michigan State 37, UCLA 21

Predictions are made by the Data Skrive betting model.

Learn more about the Michigan State Spartans vs. the UCLA Bruins game on FOX Sports!

Michigan State vs. UCLA Betting Insights

Based on the spread and over/under, the implied score for the matchup is Spartans 30, Bruins 22.
The Spartans have a 74.7% chance to win this game based on the moneyline's implied probability. The Bruins have a 29.6% implied probability.
Michigan State has covered twice in five matchups with a spread this season.
UCLA has won two games against the spread this year.

Michigan State vs. UCLA: 2025 Stats Comparison

	Michigan State	UCLA
Off. Points per Game (Rank)	32.8 (58)	19.8 (123)
Def. Points per Game (Rank)	30.6 (97)	32.4 (110)
Turnovers Allowed (Rank)	7 (74)	4 (18)
Turnovers Forced (Rank)	5 (89)	3 (120)

Michigan State 2025 Key Players

Name	Position	Stats
Aidan Chiles	QB	953 YDS (63.2%) / 9 TD / 3 INT 177 RUSH YDS / 4 RUSH TD / 35.4 RUSH YPG
Makhi Frazier	RB	325 YDS / 2 TD / 65 YPG / 4.3 YPC
Nick Marsh	WR	22 REC / 263 YDS / 3 TD / 52.6 YPG
Omari Kelly	WR	22 REC / 326 YDS / 1 TD / 65.2 YPG
Jordan Hall	LB	36 TKL / 3 TFL / 2 SACK / 1 INT
Malik Spencer	DB	21 TKL / 2 TFL / 2 SACK
Wayne Matthews III	LB	30 TKL / 1 TFL / 1 INT / 1 PD
Jalen Thompson	DL	15 TKL / 5 TFL / 2 SACK

UCLA 2025 Key Players

Name	Position	Stats
Nico Iamaleava	QB	954 YDS (66.2%) / 6 TD / 3 INT 332 RUSH YDS / 4 RUSH TD / 66.4 RUSH YPG
Kwazi Gilmer	WR	24 REC / 304 YDS / 2 TD / 60.8 YPG
Anthony Woods	RB	190 YDS / 0 TD / 38 YPG / 4.9 YPC 14 REC / 103 REC YDS / 1 REC TD / 20.6 REC YPG
Titus Mokiao-Atimalala	WR	11 REC / 126 YDS / 2 TD / 25.2 YPG
Isaiah Chisom	LB	42 TKL / 1 TFL
JonJon Vaughns	LB	45 TKL / 2 TFL
Key Lawrence	DB	24 TKL / 1 TFL
Jalen Woods	LB	21 TKL / 0 TFL / 0.5 SACK