LSU vs. Louisiana Tech Prediction, Odds, Picks - September 6, 2025

Updated Sep. 6, 2025 3:04 p.m. ET

Data Skrive

The Louisiana Tech Bulldogs (1-0) are overwhelming 36.5-point underdogs on Saturday, September 6, 2025 against the No. 3 LSU Tigers (1-0). The total has been set at 49.5 points for this game.

Against the Clemson Tigers in their last contest, the Tigers won 17-10. Against the Southeastern Louisiana Lions in their last contest, the Bulldogs won 24-0.

Keep up with college football all season on FOX Sports.

LSU vs. Louisiana Tech Game Information & Odds

When: Saturday, September 6, 2025 at 7:30 p.m. ET
Location: Tiger Stadium in Baton Rouge, Louisiana
TV: SEC Network+
Live Box Score on FOX Sports

LSU vs Louisiana Tech Betting Information updated as of September 6, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
LSU	-36.5 (-115)	-11111	+1650	49.5	-113	-106

LSU vs. Louisiana Tech Prediction

Pick ATS: Louisiana Tech (+36.5)
Pick OU: Under (49.5)
Prediction: LSU 40, Louisiana Tech 8

Predictions are made by the Data Skrive betting model.

Learn more about the LSU Tigers vs. the Louisiana Tech Bulldogs game on FOX Sports!

LSU vs. Louisiana Tech Betting Insights

Per the spread and over/under, the implied score for the game is Tigers 43, Bulldogs 6.
The Tigers have a 99.1% chance to claim victory in this meeting based on the moneyline's implied probability. The Bulldogs have a 5.7% implied probability.
LSU has a record of 1-0-0 against the spread this season.
Louisiana Tech has compiled a perfect 1-0-0 record against the spread this season.

LSU vs. Louisiana Tech: 2025 Stats Comparison

	LSU	Louisiana Tech
Off. Points per Game (Rank)	17 (95)	24 (79)
Def. Points per Game (Rank)	10 (36)	0 (1)
Turnovers Allowed (Rank)	2 (100)	0 (1)
Turnovers Forced (Rank)	1 (51)	3 (8)

LSU 2025 Key Players

Name	Position	Stats
Caden Durham	RB	74 YDS / 1 TD / 74 YPG / 4.4 YPC 3 REC / 22 REC YDS / 0 REC TD / 22 REC YPG
Garrett Nussmeier	QB	230 YDS (73.7%) / 1 TD / 0 INT
Aaron Anderson	WR	6 REC / 99 YDS / 0 TD / 99 YPG
Trey'Dez Green	TE	2 REC / 17 YDS / 1 TD / 17 YPG
PJ Woodland	DB	5 TKL / 1 TFL / 1 SACK
Harold Perkins	LB	5 TKL / 1 TFL / 1 SACK
Mansoor Delane	DB	2 TKL / 0 TFL / 1 INT / 1 PD
West Weeks	LB	5 TKL / 0 TFL

Louisiana Tech 2025 Key Players

Name	Position	Stats
Trey Kukuk	QB	126 YDS (72.2%) / 1 TD / 0 INT 48 RUSH YDS / 0 RUSH TD / 48 RUSH YPG
Clay Thevenin	RB	61 YDS / 1 TD / 61 YPG / 10.2 YPC
Omiri Wiggins	RB	1 YDS / 0 TD / 1 YPG / 0.3 YPC 1 REC / 17 REC YDS / 1 REC TD / 17 REC YPG
Eli Finley	TE	4 REC / 59 YDS / 0 TD / 59 YPG
Mekhi Mason	LB	7 TKL / 2 TFL / 2 SACK
Sifa Leota	LB	13 TKL / 2 TFL / 0.5 SACK
Kolbe Fields	LB	8 TKL / 1 TFL / 1.5 SACK
Kameron Carter	DB	2 TKL / 1 TFL / 1 SACK