College Football Top 25 Week 13 2025 Predictions, Betting Odds & TV Schedule

There are 19 games featuring a ranked team on the Week 13 college football schedule, including the No. 16 USC Trojans versus the No. 6 Oregon Ducks.

Here's everything you need to know about the betting odds for Week 13 in college football.

Check out the full college football schedule on FOX Sports! Or visit FOX Sports' college football hub for everything you need to make the most of this season’s action.

Week 13 Betting Lines & Game Info

No. 3 Texas A&M Aggies vs. Samford Bulldogs

Odds & Prediction

• Spread: Aggies (-54.5)
• Moneyline: Aggies , Bulldogs
• Total: 59.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 12 p.m. ET
• TV Channel: SEC Network+
• Location: College Station, Texas
• Box Score

Virginia Tech Hokies vs. No. 14 Miami (FL) Hurricanes

Odds & Prediction

• Spread: Hurricanes (-18.5)
• Moneyline: Hurricanes -1000, Hokies +650
• Total: 49.5 points
• Prediction: Miami (FL) 39, Virginia Tech 12

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 12 p.m. ET
• TV Channel: ESPN
• Location: Blacksburg, Virginia
• Box Score

No. 8 Oklahoma Sooners vs. No. 23 Missouri Tigers

Odds & Prediction

• Spread: Sooners (-4.5)
• Moneyline: Sooners -230, Tigers +190
• Total: 43.5 points
• Prediction: Oklahoma 30, Missouri 18

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 12 p.m. ET
• TV Channel: ABC
• Location: Norman, Oklahoma
• Box Score

No. 1 Ohio State Buckeyes vs. Rutgers Scarlet Knights

Odds & Prediction

• Spread: Buckeyes (-28.5)
• Moneyline: Buckeyes -4000, Scarlet Knights +1600
• Total: 54.5 points
• Prediction: Ohio State 42, Rutgers 9

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 12 p.m. ET
• TV Channel: FOX
• Location: Columbus, Ohio
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

No. 4 Georgia Bulldogs vs. Charlotte 49ers

Odds & Prediction

• Spread: Bulldogs (-42.5)
• Moneyline: Bulldogs , 49ers
• Total: 53.5 points
• Prediction: Georgia 54, Charlotte -1

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 12:45 p.m. ET
• TV Channel: SEC Network
• Location: Athens, Georgia
• Box Score

No. 21 James Madison Dukes vs. Washington State Cougars

Odds & Prediction

• Spread: Dukes (-14.5)
• Moneyline: Dukes -649, Cougars +470
• Total: 44.5 points
• Prediction: James Madison 31, Washington State 17

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 1 p.m. ET
• TV Channel: ESPN+
• Location: Harrisonburg, Virginia
• Box Score

No. 10 Alabama Crimson Tide vs. Eastern Illinois Panthers

Odds & Prediction

• Spread: Crimson Tide (-50.5)
• Moneyline: Crimson Tide , Panthers
• Total: 57.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 2 p.m. ET
• TV Channel: SEC Network+
• Location: Tuscaloosa, Alabama
• Box Score

No. 9 Notre Dame Fighting Irish vs. Syracuse Orange

Odds & Prediction

• Spread: Fighting Irish (-36.5)
• Moneyline: Fighting Irish , Orange
• Total: 50.5 points
• Prediction: Notre Dame 46, Syracuse 7

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 3:30 p.m. ET
• TV Channel: NBC
• Location: South Bend, Indiana
• Box Score

No. 6 Oregon Ducks vs. No. 16 USC Trojans

Odds & Prediction

• Spread: Ducks (-10.5)
• Moneyline: Ducks -410, Trojans +320
• Total: 60.5 points
• Prediction: Oregon 30, USC 25

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 3:30 p.m. ET
• TV Channel: CBS
• Location: Eugene, Oregon
• Box Score

No. 12 Vanderbilt Commodores vs. Kentucky Wildcats

Odds & Prediction

• Spread: Commodores (-7)
• Moneyline: Commodores -285, Wildcats +230
• Total: 54.5 points
• Prediction: Vanderbilt 32, Kentucky 23

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 3:30 p.m. ET
• TV Channel: ESPN
• Location: Nashville, Tennessee
• Box Score

No. 17 Texas Longhorns vs. Arkansas Razorbacks

Odds & Prediction

• Spread: Longhorns (-9.5)
• Moneyline: Longhorns -340, Razorbacks +270
• Total: 58.5 points
• Prediction: Texas 34, Arkansas 22

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 3:30 p.m. ET
• TV Channel: ABC
• Location: Austin, Texas
• Box Score

Temple Owls vs. No. 24 Tulane Green Wave

Odds & Prediction

• Spread: Green Wave (-7.5)
• Moneyline: Green Wave -270, Owls +220
• Total: 54.5 points
• Prediction: Tulane 32, Temple 23

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 3:45 p.m. ET
• TV Channel: ESPNU
• Location: Philadelphia, Pennsylvania
• Box Score

Maryland Terrapins vs. No. 18 Michigan Wolverines

Odds & Prediction

• Spread: Wolverines (-13.5)
• Moneyline: Wolverines -521, Terrapins +390
• Total: 46.5 points
• Prediction: Michigan 30, Maryland 16

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 4 p.m. ET
• TV Channel: BTN
• Location: College Park, Maryland
• Box Score

No. 13 Utah Utes vs. Kansas State Wildcats

Odds & Prediction

• Spread: Utes (-17.5)
• Moneyline: Utes -847, Wildcats +575
• Total: 52.5 points
• Prediction: Utah 39, Kansas State 14

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 4 p.m. ET
• TV Channel: ESPN2
• Location: Salt Lake City, Utah
• Box Score

No. 25 Houston Cougars vs. TCU Horned Frogs

Odds & Prediction

• Spread: Horned Frogs (-1.5)
• Moneyline: Horned Frogs -122, Cougars +102
• Total: 56.5 points
• Prediction: Houston 30, TCU 26

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 4 p.m. ET
• TV Channel: FOX
• Location: Houston, Texas
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

No. 15 Georgia Tech Yellow Jackets vs. Pittsburgh Panthers

Odds & Prediction

• Spread: Yellow Jackets (-2.5)
• Moneyline: Yellow Jackets -135, Panthers +114
• Total: 60.5 points
• Prediction: Georgia Tech 31, Pittsburgh 30

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 7 p.m. ET
• TV Channel: ESPN
• Location: Atlanta, Georgia
• Box Score

Rice Owls vs. No. 22 North Texas Mean Green

Odds & Prediction

• Spread: Mean Green (-18.5)
• Moneyline: Mean Green -1000, Owls +650
• Total: 56.5 points
• Prediction: North Texas 42, Rice 18

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 7:30 p.m. ET
• TV Channel: ESPNU
• Location: Houston, Texas
• Box Score

Florida Gators vs. No. 20 Tennessee Volunteers

Odds & Prediction

• Spread: Volunteers (-3.5)
• Moneyline: Volunteers -166, Gators +140
• Total: 58.5 points
• Prediction: Tennessee 31, Florida 26

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 7:30 p.m. ET
• TV Channel: ABC
• Location: Gainesville, Florida
• Box Score

Cincinnati Bearcats vs. No. 11 BYU Cougars

Odds & Prediction

• Spread: Cougars (-2.5)
• Moneyline: Cougars -142, Bearcats +120
• Total: 56.5 points
• Prediction: BYU 32, Cincinnati 21

How to Watch

• Game Date: Saturday, Nov. 22
• Game Time: 8 p.m. ET
• TV Channel: FOX
• Location: Cincinnati, Ohio
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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