Alabama vs. Oklahoma Prediction, Odds, Picks - November 15, 2025

Updated Nov. 15, 2025 3:04 p.m. ET

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The No. 4 Alabama Crimson Tide (8-1) and the 14th-ranked pass offense will take the field against the No. 11 Oklahoma Sooners (7-2) and the 23rd-ranked passing defense on Saturday, November 15, 2025. The Crimson Tide are favored by 6.5 points in the outing. The contest has a 45.5-point over/under.

Last time around, the Crimson Tide defeated the LSU Tigers, with 20-9 being the final score. Last time around, the Sooners defeated the Tennessee Volunteers, with 33-27 being the final score.

Keep up with college football all season on FOX Sports.

Will Alabama and Georgia solidify CFP spots this weekend with wins over SEC opponents? 🤔

Joel Klatt previewed the Texas Longhorns vs. Georgia Bulldogs and the Oklahoma Sooners vs. Alabama Crimson Tide. He analyzed how each of these teams could solidify playoff spots with wins against conference opponents. Joel explained why he trsts Georgia more over Texas and why Alabama needs to get thei rrun game going against a strong Oklahoma defense.

Alabama vs. Oklahoma Game Information & Odds

When: Saturday, November 15, 2025 at 3:30 p.m. ET
Location: Bryant-Denny Stadium in Tuscaloosa, Alabama
TV: ABC
Live Box Score on FOX Sports

Alabama vs Oklahoma Betting Information updated as of November 15, 2025, 2:46 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Alabama	-6.5 (-112)	-240	+197	45.5	-111	-109

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Alabama vs. Oklahoma Prediction

Pick ATS: Oklahoma (+6.5)
Pick OU: Over (45.5)
Prediction: Alabama 26, Oklahoma 20

Predictions are made by the Data Skrive betting model.

Learn more about the Alabama Crimson Tide vs. the Oklahoma Sooners game on FOX Sports!

Alabama vs. Oklahoma Betting Insights

Based on the spread and over/under, the implied score for the matchup is Crimson Tide 26, Sooners 20.
The Crimson Tide have a 70.6% chance to win this meeting per the moneyline's implied probability. The Sooners have a 33.7% implied probability.
Alabama has put together a 6-3-0 record against the spread this season.
Oklahoma has won five games against the spread this year, failing to cover four times.

Alabama vs. Oklahoma: 2025 Stats Comparison

	Alabama	Oklahoma
Off. Points per Game (Rank)	32.8 (47)	28.9 (68)
Def. Points per Game (Rank)	17.2 (13)	14.1 (6)
Turnovers Allowed (Rank)	6 (3)	12 (69)
Turnovers Forced (Rank)	16 (22)	7 (122)

Alabama 2025 Key Players

Name	Position	Stats
Ty Simpson	QB	2,461 YDS (66.9%) / 21 TD / 1 INT 87 RUSH YDS / 2 RUSH TD / 9.7 RUSH YPG
Germie Bernard	WR	41 REC / 605 YDS / 6 TD / 67.2 YPG
Ryan Williams	WR	36 REC / 528 YDS / 4 TD / 66 YPG
Isaiah Horton	WR	24 REC / 298 YDS / 5 TD / 37.3 YPG
Yhonzae Pierre	LB	31 TKL / 8 TFL / 6 SACK
Justin Jefferson	LB	54 TKL / 3 TFL / 2 SACK / 1 INT
Bray Hubbard	DB	43 TKL / 1 TFL / 3 INT / 3 PD
Deontae Lawson	LB	46 TKL / 0 TFL

Oklahoma 2025 Key Players

Name	Position	Stats
John Mateer	QB	1,949 YDS (63.8%) / 8 TD / 7 INT 306 RUSH YDS / 6 RUSH TD / 38.3 RUSH YPG
Isaiah Sategna	WR	49 REC / 692 YDS / 5 TD / 76.9 YPG
Tory Blaylock	RB	403 YDS / 4 TD / 44.8 YPG / 4.3 YPC
Xavier Robinson	RB	332 YDS / 4 TD / 55.3 YPG / 6.4 YPC 8 REC / 65 REC YDS / 1 REC TD / 10.8 REC YPG
R Mason Thomas	DL	21 TKL / 5 TFL / 6.5 SACK
Taylor Wein	DL	24 TKL / 10 TFL / 3.5 SACK / 1 INT
Kip Lewis	LB	41 TKL / 4 TFL / 1 SACK
Robert Spears-Jennings	DB	35 TKL / 1 TFL / 1 INT / 1 PD