Michigan vs. Duke Prediction, How to Watch, Odds, Channel - Feb 21

Updated Feb. 21, 2026 8:27 p.m. ET

FOX Sports

A pair of streaking teams meet when the No. 1 Michigan Wolverines (25-1) visit the No. 3 Duke Blue Devils (24-2) on Saturday, February 21, 2026 at 6:30 p.m. ET. The Wolverines will put their 11-game win streak on the line against the Blue Devils, winners of three straight.

The Wolverines head into their game as a 2.5-point favorite against the Blue Devils. The game features a point total of 151.5.

Keep scrolling to get all you need to know ahead of placing bets on the Michigan-Duke matchup.

Michigan vs. Duke How to Watch & Odds

When: Saturday, February 21, 2026 at 6:30 p.m. ET
Where: Capital One Arena in Washington D.C.
TV: ESPN
Streaming: FOX One + ESPN Bundle

Wolverines vs Blue Devils Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Wolverines	-2.5	-120	-107	151.5	-110	-114	-178	+146

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Michigan vs. Duke Prediction

Pick ATS: Duke (+2.5)
Pick OU: Over (151.5)
Prediction: Michigan 78, Duke 75

Learn more about the Michigan Wolverines vs. the Duke Blue Devils game on FOX Sports!

Michigan vs. Duke Betting Insights

Betting Line Implied Predictions

Per the spread and over/under, the implied score for the game is Wolverines 77, Blue Devils 74.
The Wolverines have a 64.0% chance to win this contest based on the moneyline's implied probability.
The Blue Devils hold a 40.7% implied probability to come out on top.

Key Spread Facts

Michigan has put together a 14-12-0 record against the spread this season.
Duke has put together a 14-12-0 record against the spread this year.
When playing as at least 2.5-point favorites this season, Michigan has an ATS record of 13-12.

Key Total Facts

The Wolverines and their opponent have broken the 151.5-point mark 17 times this year.
There have been 10 Blue Devils games this season with more than 151.5 points scored.
The total for this matchup is 151.5 points, 22.1 fewer than the combined scoring average of the two teams.

Key Moneyline Facts

Michigan is 24-1 in games when it was favored on the moneyline (winning 96%).
This is the first time Duke will play as an underdog this season.
Michigan has gone 22-1 when it has played as a moneyline favorite with odds of -178 or shorter (winning 95.7%).
Duke has not entered a game this season with longer moneyline odds than +146.

Michigan vs. Duke: 2025-26 Stats Comparison

	Michigan	Duke
Points Scored Per Game (Rank)	90.6 (4)	83 (46)
Points Allowed (Rank)	68.8 (60)	63.2 (3)
Rebounds (Rank)	10 (108)	10.3 (78)
3pt Made (Rank)	9.4 (65)	8.9 (97)
Assists (Rank)	19.5 (4)	16.8 (40)
Turnovers (Rank)	11.9 (262)	10.5 (121)

Michigan 2025-26 Key Players

Wolverines Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Yaxel Lendeborg	26	14.4	7.5	3.2	1.2	1.5	1.3
Morez Johnson Jr.	26	13.5	7.3	1.2	0.8	1.1	0.2
Aday Mara	26	11.2	7.1	2.5	0.4	2.7	0.1
Elliot Cadeau	26	10.1	2.7	5.5	0.7	0.1	1.7
Trey McKenney	26	10	2.7	1	0.4	0	1.7

Duke 2025-26 Key Players

Blue Devils Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Cameron Boozer	26	22.8	10	3.8	1.7	0.5	1.5
Isaiah Evans	26	14.7	3	1.2	1	0.8	2.5
Patrick Ngongba II	25	10.6	6.2	2	0.7	1.2	0.3
Caleb Foster	26	8.5	3.7	2.5	0.3	0.1	1.2
Cayden Boozer	26	6.7	2.1	2.8	0.9	0.1	0.5