Butler vs. South Carolina Prediction, How to Watch, Odds, Channel - Nov 21

Updated Nov. 21, 2025 3:27 p.m. ET

Data Skrive

The South Carolina Gamecocks (4-0) will look to extend a four-game win streak when they hit the road to take on the Butler Bulldogs (3-1) on Friday, November 21, 2025 at Colonial Hall. The matchup airs at 2 p.m. ET on CBS Sports Network.

The Bulldogs are a 3.5-point favorite against the Gamecocks when the Bulldogs and Gamecocks play. The over/under for the game is set at 150.5.

Keep reading to get the download before placing bets on the Butler-South Carolina contest.

Butler vs. South Carolina How to Watch & Odds

When: Friday, November 21, 2025 at 2 p.m. ET
Where: Colonial Hall in White Sulphur Springs, West Virginia
TV: CBS Sports Network
Live Box Score: FOX Sports

Bulldogs vs Gamecocks Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Bulldogs	-3.5	-112	-108	150.5	-112	-108	-183	+152

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Butler vs. South Carolina Prediction

Pick ATS: Pick Em
Pick OU: Over (150.5)
Prediction: Butler 82, South Carolina 79

Learn more about the Butler Bulldogs vs. the South Carolina Gamecocks game on FOX Sports!

Butler vs. South Carolina Betting Insights

Betting Line Implied Predictions

Per the spread and over/under, the implied score for the encounter is Bulldogs 77, Gamecocks 74.
The Bulldogs have a 64.7% chance to claim victory in this meeting per the moneyline's implied probability.
The Gamecocks hold a 39.7% implied probability to come out on top.

Key Spread Facts

Butler compiled a 17-18-0 record against the spread last season.
South Carolina covered 16 times in 32 chances against the spread last season.
When playing as at least a 3.5-point favorite last season, Butler had an ATS record of 6-6.
South Carolina was an underdog by 3.5 points or more 17 times last year, and covered the spread in eight of those matchups.

Key Total Facts

The Bulldogs games had more than 150.5 points on 15 occasions last year.
There were seven Gamecocks games last year with more than 150.5 points scored.
Last season, the two teams averaged a combined 144.5 points per contest, 6.0 fewer than the total for this matchup.

Key Moneyline Facts

Butler won 78.6% of the games last season in which it was favored on the moneyline (11-3).
Last season, South Carolina was the underdog 20 times and won two of those games.
When it played as a moneyline favorite with odds of -183 or shorter last year, Butler finished with a record of 9-2 (81.8%).
South Carolina did not win as an underdog of +152 or more on the moneyline last season in 17 games with those odds or longer.

Butler vs. South Carolina: 2024-25 Stats Comparison

	Butler	South Carolina
Points Scored Per Game (Rank)	74.7 (147)	69.8 (285)
Points Allowed (Rank)	74.9 (267)	71.4 (156)
Rebounds (Rank)	6.9 (327)	8.2 (237)
3pt Made (Rank)	8.5 (88)	6.7 (286)
Assists (Rank)	13.9 (148)	12.6 (250)
Turnovers (Rank)	10.4 (108)	11.8 (246)

Butler 2024-25 Top Performers

Bulldogs Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Jahmyl Telfort	33	16.0	4.7	3.4	1.0	0.3	1.3
Pierre Brooks	35	15.2	5.1	1.9	0.5	0.1	1.7
Patrick McCaffery	35	11.2	4.3	1.5	0.5	0.2	2.2
Finley Bizjack	34	10.3	2.8	2.4	0.5	0.2	1.7
Andre Screen	35	7.7	5.9	1.0	0.3	1.3	0.0

South Carolina 2024-25 Top Performers

Gamecocks Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Collin Murray-Boyles	32	16.9	8.3	2.4	1.4	1.3	0.3
Jamarii Thomas	28	13.2	2.9	3.0	1.3	0.2	1.7
Nick Pringle	32	9.5	6.3	1.1	0.5	0.4	0.0
Zachary Davis	32	8.2	4.6	1.8	1.1	0.1	0.9
Jacobi Wright	32	7.7	2.2	2.3	0.5	0.1	0.9