College Football

Penn State vs. Washington Prediction, Odds, Picks For College Football Week 10

Published Nov. 7, 2026 3:30 a.m. ET

FOX Sports Research

The Penn State Nittany Lions travel west to kick off against the Washington Huskies on Saturday in a Week 10 college football matchup on FS1.

Let’s take a look at the odds for Penn State vs. Washington at DraftKings Sportsbook as of Nov. 7.

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Penn State @ Washington Odds

Moneyline

Penn State: +114
Washington: -135

Spread

Penn State +2.5: -110
Washington -2.5: -110

Over/Under

Over 56.5: -115
Under 56.5: -105

Penn State @ Washington Prediction, Pick

From FOX Sports Research:

Penn State ended its four-game losing streak with its 12th straight win over Purdue.
Washington averages the fourth-most passing yards per game in the Big Ten (276.8)
Washington has never beaten Penn State as they are 0-4 lifetime. The last time they met was in 2024 when Penn State won 35-6.