Ohio used a balanced rushing attack, gaining 241 yards, and its defense held New Mexico State in check for a 44-24 victory in the teams' season opener.
Donte Harden led Ohio with 81 yards on 15 carries and quarterback Tyler Tettleton ran for 42 yards and two TDs.
Tettleton took over the game in the second quarter, scoring on a 1-yard run and throwing a 7-yard scoring pass to Riley Dunlop. In the third quarter, Tettleton tossed an 8-yard TD pass to Donte Foster and scored on another 1-yard run.
Tettleton completed 16 of 28 passes for 153 yards.
New Mexico State rushed for just six yards.
New Mexico State quarterback Andrew Manley threw for 362 yards and two touchdowns. Taveon Rogers scored on a 97-yard kickoff return.