Cowboys vs. Cardinals 2025 Prediction, Odds, Picks - Nov 3

Having dropped five in a row, the Arizona Cardinals (2-5) will face the Dallas Cowboys (3-4-1). The Cowboys are the favorites, expected to win by at least a field goal but less than a touchdown (currently -3.5). The over/under for this one is set at 54.5 points.

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Cowboys vs. Cardinals Odds & Betting Lines

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Cowboys vs. Cardinals Prediction & Pick

• Pick ATS: Cardinals (+3.5)
  
• Pick OU: Under (54.5)
  
• Prediction: Cowboys 28 - Cardinals 25

How to Watch Dallas vs. Arizona

• Game date: Monday, November 3, 2025
• Time: 8:15 p.m. ET
• Venue: AT&T Stadium
• Location: Arlington, Texas
• TV: ABC/ESPN
• Live Boxscore: FOX Sports

Cowboys vs. Cardinals Recent Matchups

• Over their last three meetings, Arizona has tallied two wins against Dallas.
• Over their last three head-to-head contests, Arizona has scored 70 points, while Dallas has accumulated 66.

Dallas Betting Info

• Against the spread, Dallas is 4-4-0 this season.
• The Cowboys have been favored by 3.5 points or more this season twice, and failed to cover both times.
• Dallas games this year have hit the over on six of eight set point totals (75%).
• The Cowboys have a 2-2 record in games they played as the moneyline favorite (winning 50% of those games).
• Based on this contest's moneyline, the Cowboys' implied win probability is 63.6%.

Cowboys Stats

Dallas' Key Players

Offense

• Dak Prescott ranks eighth in the NFL with 2,069 passing yards through eight games this year, averaging 258.6 per game with a 70.3% completion percentage and 16 touchdowns (eighth in the NFL) against five interceptions.
• He has added 87 rushing yards (10.9 per game) and one touchdown on the ground.
• Javonte Williams has racked up 633 rushing yards (fifth in the NFL) with eight touchdowns (79.1 yards per game across eight games). His 5.1 yards per attempt rank sixth in the NFL.
• Williams' 34 targets through the air have resulted in 24 catches (three per game) for 93 yards (11.6 per game) and one touchdown.
• Through eight games played, George Pickens is averaging 85.6 yards and 5.4 receptions per game on the way to 685 receiving yards (fourth in the NFL) and 43 catches. He's been targeted 63 times, and has six receiving touchdowns (fourth in the NFL).
• Jake Ferguson averages 6.4 receptions and 41.8 yards per game, and has 334 total receiving yards and 51 catches (eighth in the NFL). He's gotten 59 total targets, and has caught six touchdown passes (fourth in the NFL).

Defense

• Over on the defensive side, Kenneth Murray has 58 tackles, four TFL, and one sack in 2025.
• Shemar James has 42 tackles, one TFL, and one sack this season.
• This season, James Houston has put up 3.5 sacks (first on the Cowboys) in addition to his four TFL and 13 tackles.
• So far this season, Donovan Wilson has 36 tackles and two interceptions.

Arizona Betting Info

• Arizona has covered the spread in a game four times this season (4-3-0).
• The Cardinals have been underdogs by 3.5 points or more two times this year and have covered the spread every time.
• Arizona games have gone over the total four times this season.
• The Cardinals have been listed as the underdog four times this season and have failed to win any of those games.
• Bookmakers have implied with the moneyline set for this matchup that the Cardinals have a 40.8% chance to win.

Cardinals Stats

Arizona's Key Players

Offense

• Kyler Murray has thrown for 962 yards this year, with six touchdowns and three interceptions. He is completing 68.3% of his passes while averaging 192.4 yards per game and 6 per attempt.
• On the ground, Kyler Murray has added one rushing touchdown and 173 rushing yards (first on the Cardinals).
• Trey McBride has 421 receiving yards and four touchdowns on 47 receptions (10th in the NFL), while being targeted 66 times.
• This season, Marvin Harrison Jr. has caught 24 passes for 396 receiving yards with two touchdowns in the passing game. He has been targeted 40 total times and is averaging 3.4 receptions per game through seven games played.
• Jacoby Brissett has 599 passing yards, four touchdowns and one interception. His completion percentage is 64.2% and he averages 149.8 yards per game and 7.4 per attempt.
• He has also added 47 rushing yards (seventh on the Cardinals), with zero touchdowns on the ground (averaging 11.8 yards per game and 4.7 per carry).

Defense

• Mack Wilson has intercepted one pass and also has 53 tackles, three TFL, and six passes defended in 2025.
• Josh Sweat has 15 tackles, seven TFL, five sacks, and one pass defended.
• Akeem Davis-Gaither has 40 tackles and one TFL in the 2025 campaign. He is fourth on the Cardinals in tackles.
• Jalen Thompson has registered one TFL and 48 tackles through seven games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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