2025 NFL Week 12 Predictions, Betting Odds & TV Schedule

The NFL schedule in Week 12 is sure to please. The matchups include the Tampa Bay Buccaneers playing the Los Angeles Rams at SoFi Stadium.

With Week 12 in the NFL upon us, stay on top of the most current betting trends with our preview below.

Check out the full NFL schedule on FOX Sports!

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Week 12 Betting Lines & Game Info

Houston Texans vs. Buffalo Bills

Odds & Prediction

• Spread: Bills (-5.5)
• Moneyline: Bills -265, Texans +216
• Total: 44.5 points
• Prediction: Texans 26, Bills 19

How to Watch

• Game Date: Thursday, Nov. 20
• Game Time: 8:15 p.m. ET
• TV Channel: Amazon Prime Video
• Box Score
• Location: Houston, Texas

Cincinnati Bengals vs. New England Patriots

Odds & Prediction

• Spread: Patriots (-7.5)
• Moneyline: Patriots -386, Bengals +303
• Total: 50.5 points
• Prediction: Patriots 32, Bengals 19

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Cincinnati, Ohio

Chicago Bears vs. Pittsburgh Steelers

Odds & Prediction

• Spread: Bears (-2.5)
• Moneyline: Bears -152, Steelers +128
• Total: 46.5 points
• Prediction: Bears 26, Steelers 24

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Chicago, Illinois

Kansas City Chiefs vs. Indianapolis Colts

Odds & Prediction

• Spread: Chiefs (-4.5)
• Moneyline: Chiefs -217, Colts +179
• Total: 49.5 points
• Prediction: Colts 25, Chiefs 24

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Kansas City, Missouri

Detroit Lions vs. New York Giants

Odds & Prediction

• Spread: Lions (-13.5)
• Moneyline: Lions -1087, Giants +685
• Total: 50.5 points
• Prediction: Lions 32, Giants 18

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Detroit, Michigan

Baltimore Ravens vs. New York Jets

Odds & Prediction

• Spread: Ravens (-14)
• Moneyline: Ravens -1190, Jets +735
• Total: 44.5 points
• Prediction: Ravens 32, Jets 17

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Baltimore, Maryland

Tennessee Titans vs. Seattle Seahawks

Odds & Prediction

• Spread: Seahawks (-12.5)
• Moneyline: Seahawks -885, Titans +594
• Total: 41.5 points
• Prediction: Seahawks 31, Titans 14

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Nashville, Tennessee

Green Bay Packers vs. Minnesota Vikings

Odds & Prediction

• Spread: Packers (-6.5)
• Moneyline: Packers -288, Vikings +234
• Total: 41.5 points
• Prediction: Packers 26, Vikings 18

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Green Bay, Wisconsin

Arizona Cardinals vs. Jacksonville Jaguars

Odds & Prediction

• Spread: Jaguars (-2.5)
• Moneyline: Jaguars -132, Cardinals +112
• Total: 47.5 points
• Prediction: Jaguars 27, Cardinals 21

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Glendale, Arizona

Las Vegas Raiders vs. Cleveland Browns

Odds & Prediction

• Spread: Raiders (-3)
• Moneyline: Raiders -171, Browns +142
• Total: 36 points
• Prediction: Raiders 22, Browns 19

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Paradise, Nevada

Dallas Cowboys vs. Philadelphia Eagles

Odds & Prediction

• Spread: Eagles (-3)
• Moneyline: Eagles -162, Cowboys +136
• Total: 47.5 points
• Prediction: Eagles 30, Cowboys 21

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Arlington, Texas

New Orleans Saints vs. Atlanta Falcons

Odds & Prediction

• Spread: Saints (-1.5)
• Moneyline: Saints -124, Falcons +104
• Total: 41 points
• Prediction: Saints 22, Falcons 20

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: New Orleans, Louisiana

Los Angeles Rams vs. Tampa Bay Buccaneers

Odds & Prediction

• Spread: Rams (-7)
• Moneyline: Rams -370, Buccaneers +293
• Total: 49.5 points
• Prediction: Rams 31, Buccaneers 17

How to Watch

• Game Date: Sunday, Nov. 23
• Game Time: 8:20 p.m. ET
• TV Channel: NBC/Peacock
• Box Score
• Location: Inglewood, California

San Francisco 49ers vs. Carolina Panthers

Odds & Prediction

• Spread: 49ers (-7.5)
• Moneyline: 49ers -370, Panthers +292
• Total: 49.5 points
• Prediction: 49ers 29, Panthers 15

How to Watch

• Game Date: Monday, Nov. 24
• Game Time: 8:15 p.m. ET
• TV Channel: ESPN
• Box Score
• Location: Santa Clara, California

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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