Lakers vs. Spurs Prediction, Odds, Picks - Nov. 5

The Los Angeles Lakers (6-2) hope to build on a four-game winning streak when they host the San Antonio Spurs (5-1) on November 5, 2025 at Crypto.com Arena. Los Angeles is a slim 1-point favorite against San Antonio when the Lakers take on the Spurs on Wednesday. The over/under is 227.5 points for the game.

Take a look at everything you need to know to know about the Lakers-Spurs game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Lakers vs. Spurs Game Information, TV Channel & Odds

• When: Wednesday, November 5, 2025 at 10 p.m. ET
• Where: Crypto.com Arena in Los Angeles, California
• TV: ESPN, SportsNet LA, and FDSSW
• Live Boxscore: FOX Sports

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Lakers vs. Spurs Prediction

ATS Pick: Lakers (- 1)
O/U Pick: Over (227.5)
Score Prediction: Lakers 118 - Spurs 114

Lakers vs. Spurs Betting Insights

• The Lakers and their opponent have combined to go over 227.5 points scored, the current matchup's over/under, in every game this season.
• Two of the Spurs' six games this season have had more than 227.5 total points scored.
• The two teams average a combined 10.5 more points per game, 238, than this matchup's over/under of 227.5 points.
• Opponents of these two teams have averaged a combined 224.8 points per game, 2.7 fewer than the over/under for this matchup.
• Los Angeles has won in each of the two contests it has played as odds-on favorites this season.
• San Antonio came away victorious in the one game it played as the underdog this season.
• Los Angeles has won three of its last four head-to-head meetings with San Antonio.
• The Lakers have an advantage against the spread as well (3-1) when playing the Spurs.
• In their past four contests the Lakers have beaten the point spread, and they were the favorites in two of those games.

Lakers Recent Trends

• In the Lakers' eight games this year, they have six wins against the spread.
• Los Angeles has been favored by 1 point or more two times this season and have covered the spread in all of them.
• The Lakers have gone over the point total in 116.7% of their opportunities this year (seven times over six games with a set point total).
• The Lakers score 11.6 more points per game (119.8) than the Spurs give up (108.2).
• Los Angeles has a 6-1 record against the spread and a 6-1 record overall when putting up more than 108.2 points.
• This season, the Lakers have a 52.9% shooting percentage from the field, which is 8.4% higher than the 44.5% of shots the Spurs' opponents have hit.
• The Lakers have covered the spread in a lower percentage of their home games than road games. They have covered two times in four games when playing at home, and they've covered four times in four games on the road.
• Los Angeles has hit the over on the total in four of four home games (100%), compared to three of four road games (75%).
• The Lakers, as a moneyline favorite, have an identical winning percentage when playing at home (1-0 record) and on the road (1-0 record).

Lakers Recent Stats

Lakers Leaders

• Luka Doncic puts up 41.3 points, 11.5 rebounds and 8.3 assists per contest. Defensively, he averages 1.3 steals and 0.3 blocks.
• Jake Laravia averages 12.6 points, 3 assists and 5.1 boards per contest.
• Deandre Ayton puts up 16.9 points, 8.1 boards and 1.3 assists per contest, shooting 65.1% from the field (fifth in NBA).
• Rui Hachimura posts 16.9 points, 4.1 boards and 1.8 assists per game. Defensively, he averages 0.5 steals and 0.4 blocks.
• Jarred Vanderbilt posts 4.8 points, 5.9 rebounds and 1.5 assists per contest, shooting 43.3% from the field.

Lakers Player Props

Spurs Recent Trends

• The Spurs have two wins against the spread in six games this year.
• San Antonio covered the spread in its only game when underdogs by 1 point or more.
• Spurs games this season have hit the over on two of six set point totals.
• The Spurs put up an average of 118.2 points per game, just 1.6 more points than the 116.6 the Lakers give up to opponents.
• When it scores more than 116.6 points, San Antonio is 2-2-1 against the spread and 4-1 overall.
• The Spurs are shooting 49.8% from the field, 2.5% higher than the 47.3% the Lakers' opponents have shot this season.

Spurs Recent Stats

Spurs Leaders

• Victor Wembanyama puts up 26.7 points, 13.7 rebounds and 3.2 assists per game for the Spurs.
• Stephon Castle is averaging 20 points, 6.2 rebounds and 5.3 assists per game. He's sinking 55.4% of his shots from the field and 34.6% from 3-point range, with 1.5 triples per contest.
• The Spurs are receiving 14.7 points, 4.3 rebounds and 2.3 assists per game from Devin Vassell this season.
• Keldon Johnson gives the Spurs 13 points, 5.3 rebounds and 1.2 assists per game while putting up 0.5 steals and 0 blocked shots.
• The Spurs are getting 7.5 points, 6.2 rebounds and 1.8 assists per game from Julian Champagnie this season.

Spurs Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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