Twins vs. Guardians Prediction, Odds, Picks - April 4

Pablo Lopez and Tanner Bibee are the scheduled starters when the Minnesota Twins and Cleveland Guardians meet on Thursday at Target Field, at 4:10 PM ET. Bookmakers list the Twins as -166 favorites on the moneyline, while giving the underdog Guardians +138 moneyline odds to win. Minnesota is the run-line favorite (-1.5). The over/under is 7 runs for the contest (with -113 odds on the over and -106 odds to go under).

Check out everything you need from a betting perspective on the Twins-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Twins vs. Guardians Game Information & Odds

• When: Thursday, April 4, 2024 at 4:10 PM ET
• Where: Target Field in Minneapolis, Minnesota
• How to Watch on TV: BSN

Twins vs. Guardians Prediction

• Score Prediction: Twins 4, Guardians 3
• Total Prediction: Under 7 runs
• Win Probabilities: Twins 51%, Guardians 49%

Twins vs. Guardians Betting Insights

• The Twins won 59.5% of the games last season they were the moneyline favorite (69-47).
• Minnesota had a record of 24-17 when playing as a moneyline favorite with odds of -166 or shorter last year (58.5%).
• The Twins have a 62.4% chance to win this matchup based on the moneyline's implied probability.
• Last season, the Guardians won 36 out of the 81 games, or 44.4%, in which they were the underdog.

Twins Player Insights

• Carlos Santana finished last season with a .240 average and 86 RBI.
• Max Kepler finished with a .484 SLG and 24 homers while driving in 66 runs.
• Carlos Correa finished last season with 18 home runs, 65 RBI and a batting average of .230.
• Willi Castro collected 92 hits, posted an OBP of .339 and a .411 SLG.

Twins Team Props

Learn more about this Twins vs. Guardians matchup on Fox Sports.

Guardians Player Insights

• Andres Gimenez has driven in a team-leading six runs batted in.
• Gimenez's home run total places him 144th in the big leagues, and he ranks 23rd in RBI.
• Jose Ramirez has been a reliable source of runs this year, leading the lineup with one home runs and six runs batted in.
• Ramirez ranks 44th in home runs and 23rd in RBI among all hitters in the big leagues.
• Steven Kwan paces the Guardians with one long balls while accruing a team-high batting average of .353.
• Josh Naylor has racked up a team-high one home runs.

Guardians Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.