Tigers vs. White Sox Prediction, Odds, Picks - September 6

Andrew Benintendi and the Chicago White Sox take on Gleyber Torres and the Detroit Tigers at Comerica Park on Saturday at 6:10 p.m. ET. The White Sox are listed as +243 moneyline underdogs in this matchup against the favored Tigers (-305). Detroit is the favorite on the run line (-1.5 with -135 odds). The total is 7.5 runs for this contest (with +101 odds to hit the over and -124 odds on the under).

Here's everything you need to know from a betting perspective on the Tigers-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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White Sox vs. Tigers Highlights | MLB on FOX

Check out the best highlights between the Chicago White Sox and the Detroit Tigers.

Tigers vs. White Sox Game Information & Odds

• When: Saturday, September 6, 2025 at 6:10 p.m. ET
• Where: Comerica Park in Detroit, Michigan
• How to watch on TV: FDSDET and CHSN

Tigers vs. White Sox Prediction

• Score Prediction: Tigers 4, White Sox 3
• Total Prediction: Under 7.5 runs
• Win Probabilities: Tigers 58%, White Sox 42%

Tigers vs. White Sox Betting Insights

• This season, the Tigers have won 61 out of the 99 games, or 61.6%, in which they've been favored.
• Detroit is undefeated in three games this season when favored by -305 or more on the moneyline.
• The implied probability of a win from the Tigers, based on the moneyline, is 75.3%.
• The White Sox have been underdogs in 140 games this season and have come away with the win 53 times (37.9%) in those contests.
• Chicago has won all of its four games in which it was named as at least a +243 moneyline underdog.
• The White Sox have an implied victory probability of 29.2% according to the moneyline set by oddsmakers for this matchup.

Tigers Recent Betting Performance

• The Tigers played as the moneyline favorite for six of their last 10 games, and they finished 1-5 in those matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Tigers and their opponents combined to hit the over five times.
• The Tigers' ATS record is 3-7-0 over their past 10 games.

Tigers Recent Stats

Tigers Player Insights

• Riley Greene's 32 home runs and 103 RBI both lead the Tigers, in addition to his team-high .269 average.
• Of all batters in MLB, Greene is 10th in homers and fifth in RBI.
• Greene has collected a hit in two games in a row. During his last five outings he is batting .263 with a double, two walks and two RBIs.
• Torres is hitting .258 with 19 doubles, 14 home runs and 73 walks.
• Torres is 133rd in home runs in MLB, and 82nd in RBI.
• Spencer Torkelson is batting .238 with 26 doubles, a triple, 28 home runs and 62 walks.
• Torkelson will look to build on his four-game hitting in this matchup. In his last five games he is hitting .278 with a double, two walks and two RBIs.
• Zach McKinstry has 20 doubles, 11 triples, 11 home runs and 45 walks while hitting .267.
• McKinstry is riding a five-game hitting streak into this one. In his last five games he is hitting .412 with two doubles, a triple, two walks and three RBIs.

Tigers Team Props

White Sox Recent Betting Performance

• In 10 games over the last 10 matchups when set as underdogs by oddsmakers, the White Sox had a record of 6-4.
• The White Sox and their opponents have combined to hit the over seven times in their last 10 games with a total.
• The White Sox have six wins against the spread in their last 10 chances.

White Sox Recent Stats

White Sox Player Insights

• Benintendi has 15 doubles, two triples, 18 home runs and 35 walks while hitting .244.
• Among all hitters in the big leagues, Benintendi's home run total is 84th and his RBI tally ranks 109th.
• Lenyn Sosa proven to be a run producer as he paces his team with 19 home runs and 62 RBI, with a team-best .263 batting average.
• Sosa is currently 70th in home runs and 87th in RBI in the major leagues.
• Chase Meidroth is hitting .259 with 15 doubles, four home runs and 38 walks.
• Mike Tauchman has 15 doubles, a triple, eight home runs and 40 walks while batting .271.

White Sox Team Props

White Sox vs. Tigers Highlights | MLB on FOX

Check out the best highlights between the Chicago White Sox and the Detroit Tigers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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