Royals vs. Mariners Prediction, Odds, Picks - September 17

Julio Rodriguez and the Seattle Mariners hit the field on Wednesday at Kauffman Stadium against Cole Ragans, who will start for the Kansas City Royals. First pitch is set for 7:40 p.m. ET. The Royals are -124 moneyline favorites for this matchup against the Mariners (+104). Kansas City is favored on the run line (-1.5). The over/under is 8.5 runs for the game (with -120 odds to go over and -100 odds on the under).

Here is everything you need from a betting perspective on the Royals-Mariners game, regarding the run line, moneyline and total, plus expert picks.

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Royals vs. Mariners Game Information & Odds

• When: Wednesday, September 17, 2025 at 7:40 p.m. ET
• Where: Kauffman Stadium in Kansas City, Missouri
• How to watch on TV: FDSKC and ROOT Sports NW

Royals vs. Mariners Prediction

• Score Prediction: Royals 6, Mariners 5
• Total Prediction: Over 8.5 runs
• Win Probabilities: Royals 50%, Mariners 50%

Royals vs. Mariners Betting Insights

• This season, the Royals have been favored 63 times and won 36, or 57.1%, of those games.
• Kansas City is 25-17 this season when entering a game favored by -124 or more on the moneyline.
• The implied probability of a win from the Royals, based on the moneyline, is 55.4%.
• The Mariners have been victorious in 21, or 47.7%, of the 44 contests they have been chosen as underdogs in this season.
• Seattle has a win-loss record of 15-13 when favored by +104 or worse by sportsbooks this year.
• The Mariners have an implied victory probability of 49% according to the moneyline set by sportsbooks for this matchup.

Royals Recent Betting Performance

• The Royals have been listed as the moneyline favorite by bookmakers only once in the last 10 games, and lost that matchup.
• Over their last 10 outings (all 10 of them had set totals), the Royals and their opponents combined to go over the run total six times.
• The Royals have a 3-7-0 record against the spread over their past 10 games.

Royals Recent Stats

Royals Player Insights

• Bobby Witt Jr. has racked up a team-best batting average of .292.
• Witt's home runs place him 58th in MLB, and he is 44th in RBI.
• Witt carries a two-game hitting streak into this matchup. In his last five games he is hitting .211 with a triple, a home run, two walks and two RBIs.
• Maikel Garcia has 36 doubles, five triples, 16 home runs and 57 walks while hitting .289.
• Garcia is 117th in homers and 74th in RBI among all major league hitters this season.
• Vinnie Pasquantino paces the Royals with 30 home runs and 104 runs batted in.
• Salvador Perez is hitting .237 with 34 doubles, 28 home runs and 23 walks.
• Perez brings a three-game streak with at least one hit into this one. During his last five outings he is batting .273 with three home runs and eight RBIs.

Royals Team Props

Mariners Recent Betting Performance

• Over the past 10 games, the Mariners have been underdogs just once and won that contest.
• The Mariners and their opponents have combined to hit the over seven times in their last 10 games with a total.
• The Mariners have won eight of their last 10 games against the spread.

Mariners Recent Stats

Mariners Player Insights

• Cal Raleigh has put up a team-leading 56 home runs and has driven in 118 runs.
• Among all hitters in the big leagues, Raleigh is first in home runs and second in RBI.
• Raleigh has collected a hit in four straight games. In his last five games he is batting .444 with three doubles, three home runs, five walks and five RBIs.
• Rodriguez is batting .271 with 31 doubles, four triples, 30 home runs and 38 walks.
• Among all MLB batters, Rodriguez is 16th in homers and 18th in RBI.
• Josh Naylor leads the Mariners with a team-high batting average of .283.
• Eugenio Suarez is batting .224 with 25 doubles, 45 home runs and 44 walks.

Mariners Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Kansas City Royals

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